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MCP Joint Arthritis

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MCP Joint Arthritis

Comprehensive guide to MCP joint arthritis including rheumatoid arthritis, post-traumatic arthritis, primary OA, clinical presentation, non-operative management, and surgical options including arthroplasty and arthrodesis for orthopaedic fellowship exam preparation.

complete
Updated: 2025-12-25
High Yield Overview

MCP JOINT ARTHRITIS

Metacarpophalangeal Joint Degenerative and Inflammatory Arthritis

90%
—prevalence
—blue

Classifications

Larsen
PatternRadiographic Grading (I-V)
TreatmentSeverity Assessment
Nalebuff
PatternDeformity Patterns
TreatmentReconstruction Planning

Critical Must-Knows

  • Mechanism: Rheumatoid: chronic synovitis causes capsular and ligament stretch leading to volar subluxation and ulnar drift with extensor tendon displacement
  • Management: Non-operative: DMARDs (methotrexate first-line), biologics for severe RA, NSAIDs, corticosteroid injections, splinting
  • Key point requiring clinical understanding

Examiner's Pearls

  • "
    Exam point to remember
  • "
    Exam point to remember
  • "
    Exam point to remember

Clinical Imaging

Imaging Gallery

Bone erosions in a patient with rhupus syndrome. Longitudinal ultrasound image of the second metacarpophalangeal joint lateral area showing a grade-2 scoring ultrasound structural erosion (arrow) with
Click to expand
Bone erosions in a patient with rhupus syndrome. Longitudinal ultrasound image of the second metacarpophalangeal joint lateral area showing a grade-2 Credit: Open-i / NIH via Open-i (NIH) (Open Access (CC BY))
Signs of destruction and inflammation on ultrasonography and MRI in second metacarpophalangeal joint: established RA. Thin arrows indicate an erosive change; thick arrows indicate synovitis. Ultrasono
Click to expand
Signs of destruction and inflammation on ultrasonography and MRI in second metacarpophalangeal joint: established RA. Thin arrows indicate an erosive Credit: Szkudlarek M et al. via Arthritis Res. Ther. via Open-i (NIH) (Open Access (CC BY))
Contrast-enhanced T1-weighted magnetic resonance imaging of metacarpophalangeal (MCP) joints 2 and 3 and maximum synovial enhancement of MCP 2. Illustration of contrast-enhanced T1-weighted magnetic r
Click to expand
Contrast-enhanced T1-weighted magnetic resonance imaging of metacarpophalangeal (MCP) joints 2 and 3 and maximum synovial enhancement of MCP 2. IllustCredit: Vordenbäumen S et al. via Arthritis Res. Ther. via Open-i (NIH) (Open Access (CC BY))
Not Available.
Click to expand
Not Available.Credit: Elenbaum SLE et al. via MedPix via Open-i (NIH) (Open Access (CC BY))

Critical MCP Arthritis Exam Points

Rheumatoid MCP Pathomechanics

Synovitis stretches volar plate and collateral ligaments. MCP subluxes volarly and ulnarly. Extensor tendons displace ulnarly into valleys between MCPs. Results in ulnar drift deformity. Know mechanism: VUSEX (Volar, Ulnar, Synovitis, Extensor, X-ray).

Silicone Arthroplasty Principles

Silicone spacer arthroplasty is standard for MCP arthritis (digits 2-5). NOT a load-bearing hinge - acts as flexible spacer. Fibrous encapsulation provides stability. Restores alignment, preserves 30-40 degrees motion. 10-15 year survivorship. Adjunct soft tissue balancing essential.

Thumb MCP Management

Arthrodesis preferred for thumb MCP arthritis. Provides stable lateral key pinch and pulp pinch. Fusion position: 10-15 degrees flexion, neutral rotation. Arthroplasty risks instability with high pinch loads. Plate fixation preferred over K-wires. 95% fusion rate.

Soft Tissue Balancing

Correct ALL pathology, not just bone. Synovectomy for active rheumatoid disease, extensor tendon centralization (reposition over MCP center), radial collateral ligament reconstruction (correct ulnar drift), intrinsic release if tight. Arthroplasty alone WILL fail without soft tissue balancing.

At a Glance

MCP joint arthritis is predominantly rheumatoid (90% of RA patients affected), presenting with the classic volar subluxation and ulnar drift deformity caused by chronic synovitis stretching the volar plate and collateral ligaments. Surgical management differs by digit: silicone arthroplasty for digits 2-5 (acts as flexible spacer, not load-bearing, provides 30-40° motion arc with 10-15 year survivorship), while arthrodesis is preferred for the thumb MCP (10-15° fusion position for stable pinch). Critical principle: soft tissue balancing is essential - synovectomy, extensor centralisation, radial collateral ligament reconstruction, and intrinsic release must accompany arthroplasty or it will fail.

Mnemonic

VUSEXRheumatoid MCP Deformity Mechanism

V
V - Volar subluxation (proximal phalanx subluxes volarly)
U
U - Ulnar drift (fingers deviate ulnarly from ligament laxity)
S
S - Synovitis (primary pathology - chronic inflammation)
E
E - Extensor displacement (tendons displace ulnarly into valleys)
X
X - X-ray shows subluxation (diagnostic confirmation)

Memory Hook:VUSEX captures the rheumatoid MCP mechanism - examiners expect you to describe this sequence!

Mnemonic

SPACERSilicone Arthroplasty Principles

S
S - Silicone elastomer (flexible, not load-bearing)
P
P - Preserves motion (30-40 degrees flexion arc)
A
A - Alignment restored (corrects ulnar drift and volar subluxation)
C
C - Centralize extensors (rebalance over MCP center)
E
E - Encapsulation (fibrous capsule forms around implant)
R
R - Release intrinsics (tight ulnar intrinsics must be released)

Memory Hook:SPACER - silicone acts as a spacer, not a true joint replacement!

Mnemonic

CASCADEMCP Arthrodesis Fusion Positions

C
C - Cascading flexion (ulnar digits progressively more flexed)
A
A - Angle for thumb: 10-15 degrees flexion
S
S - Small finger most flexed: 45-50 degrees
C
C - Check pinch position intraoperatively
A
A - Avoid excessive flexion or hyperextension
D
D - Digits 2-5: Index 25-30, Middle 35-40, Ring 40-45, Small 45-50
E
E - Essential for grip function (mimics normal hand cascade)

Memory Hook:CASCADE reminds you of the cascading flexion pattern from radial to ulnar!

Overview and Epidemiology

Why MCP Arthritis Matters in Exams

MCP joint arthritis is predominantly rheumatoid. Examiners expect detailed knowledge of rheumatoid pathomechanics (synovitis leading to volar subluxation and ulnar drift), surgical decision-making (silicone arthroplasty for digits 2-5, arthrodesis for thumb), and adjunct soft tissue procedures (extensor centralization, ligament reconstruction). This is a pattern recognition and surgical planning topic.

MCP Joint Arthritis is inflammation and degeneration of the metacarpophalangeal joints, presenting as pain, stiffness, deformity, and functional impairment.

Epidemiology

Rheumatoid Arthritis (Most Common)

Prevalence:

  • 90% of RA patients develop MCP involvement
  • Bilateral and symmetric distribution
  • Female greater than male (3:1 ratio)
  • Peak onset 40-60 years of age
  • Progression over years to decades

Natural History:

  • Early: synovitis, pain, morning stiffness
  • Moderate: ulnar drift, volar subluxation
  • Late: severe deformity, extensor tendon displacement, functional disability

Post-Traumatic and Other Causes

Post-Traumatic Arthritis:

  • Following MCP fracture with articular involvement
  • Chronic MCP instability from collateral ligament injury
  • Prior MCP dislocation
  • Usually unilateral, single digit

Primary Osteoarthritis:

  • Rare at MCP (unlike CMC-1, DIP, PIP joints)
  • More common in manual laborers
  • Typically less severe than rheumatoid

Other Inflammatory:

  • Psoriatic arthritis (seronegative, DIP and MCP)
  • Crystalline arthropathy (gout, pseudogout)

Risk Factors

Rheumatoid Arthritis:

  • Autoimmune predisposition (RF positive, anti-CCP antibodies)
  • Genetic factors (HLA-DR4, family history)
  • Female sex, smoking history
  • Environmental triggers (infections, hormonal changes)

Post-Traumatic:

  • Intra-articular MCP fracture (especially volar plate avulsion)
  • Chronic MCP instability (collateral ligament injury)
  • Dorsal MCP dislocation with articular damage
  • Inadequate initial treatment of MCP injuries

Occupational:

  • Repetitive gripping and pinching (manual laborers)
  • Vibratory tool use
  • Heavy manual work

Anatomy and Biomechanics

MCP Joint Architecture

Cam and Post Configuration:

  • Metacarpal head: Cam-shaped (eccentric condyle)
  • Wider volarly than dorsally (approximately 20-30% larger volar diameter)
  • Proximal phalanx base: Shallow concave (post)
  • Articular mismatch: Allows increased ROM but inherent instability

Collateral Ligaments:

  • Proper collateral ligament: Origin at metacarpal head dorsal to axis of rotation, inserts on proximal phalanx base
  • Accessory collateral ligament: Origin at metacarpal, inserts on volar plate
  • Function: Lax in extension (allows lateral deviation), tight in flexion (stabilizes joint)
  • In rheumatoid: Stretched by synovitis, leading to instability

Volar Plate:

  • Thick fibrocartilaginous structure on palmar aspect
  • Prevents MCP hyperextension
  • Attachment: Weak proximally (allows volar subluxation in RA), strong distally to proximal phalanx
  • In rheumatoid: Stretched, allowing volar subluxation of proximal phalanx

Extensor Mechanism:

  • Extensor digitorum communis: Inserts on proximal phalanx base via extensor hood
  • Sagittal bands: Stabilize extensor tendon over MCP center (radial and ulnar bands)
  • In rheumatoid: Sagittal bands attenuate, extensor displaces ulnarly into valley between MCP heads

Biomechanics of Normal MCP Function

Range of Motion:

  • Flexion: 80-90 degrees (digits 2-5), 50-60 degrees (thumb)
  • Extension: 0-20 degrees hyperextension (normal variation)
  • Radial-ulnar deviation: 10-20 degrees in extension (lax collaterals), minimal in flexion

Stability:

  • Bony congruity: Minimal (cam and post mismatch)
  • Static stabilizers: Collateral ligaments, volar plate, joint capsule
  • Dynamic stabilizers: Intrinsic muscles (lumbricals, interossei), extensor tendons

Load Transmission:

  • Power grip: High compressive loads across MCPs (up to 5-10 times grip force)
  • Precision pinch: Index and thumb MCPs experience high loads
  • Implication: Thumb MCP requires arthrodesis for pinch stability (arthroplasty fails under load)

Pathophysiology and Deformity Mechanisms

Rheumatoid MCP Deformity Mechanism (VUSEX)

Volar subluxation and Ulnar drift result from Synovitis causing capsular stretch, with Extensor tendon displacement ulnarly, confirmed on X-ray. This is the pathomechanical sequence examiners expect you to recite.

Rheumatoid Arthritis MCP Deformity

Sequential Pathomechanics:

  1. Synovitis (Primary Event):

    • Chronic inflammation of MCP synovium
    • Pannus formation (invasive synovial tissue)
    • Release of inflammatory cytokines (TNF-alpha, IL-1, IL-6)
    • Enzymatic degradation of cartilage (matrix metalloproteinases)
  2. Capsular and Ligament Stretch:

    • Synovial hypertrophy distends joint capsule
    • Radial collateral ligament stretches (allows ulnar drift)
    • Volar plate stretches proximally (allows volar subluxation)
    • Sagittal bands attenuate (allows extensor tendon displacement)
  3. Volar Subluxation:

    • Proximal phalanx subluxes volarly on metacarpal head
    • Visible step-off at MCP dorsally
    • Loss of normal MCP contour
    • Worsens with grip activities (force vector pulls phalanx volarly)
  4. Ulnar Drift:

    • Radial collateral ligament laxity allows ulnar deviation
    • Ulnar intrinsic muscles (ulnar lumbricals, interossei) pull digits ulnarly
    • Wrist radial deviation compounds MCP ulnar drift (Z-collapse deformity)
    • Gravity and grip forces perpetuate ulnar deviation
  5. Extensor Tendon Displacement:

    • Sagittal band attenuation allows extensor to displace ulnarly
    • Extensor falls into valley between MCP heads
    • Acts as ulnar deviator instead of pure extensor
    • Creates extensor lag and perpetuates ulnar drift
  6. Progressive Deformity:

    • Biomechanical imbalance worsens with hand use
    • Deformity becomes fixed (contracture)
    • Articular cartilage erosion from abnormal loading
    • End-stage: mutilating arthropathy

Nalebuff Rheumatoid Hand Classification:

TypeDeformity PatternMechanismTreatment Consideration
Type ISwan-neck (MCP flex, PIP hyperextension, DIP flexion)Intrinsic tightness, PIP volar plate laxity, FDS weaknessAddress MCP and PIP (may need PIP fusion or reconstruction)
Type IIBoutonniere (MCP hyperextension, PIP flexion, DIP hyperextension)Central slip rupture at PIP, lateral band volar displacementPIP central slip reconstruction or fusion
Type IIIMCP ulnar drift with swan-neckCombined Type I and MCP pathologyMCP arthroplasty with PIP management
Type IVSevere MCP volar subluxationEnd-stage rheumatoid destructionMCP arthroplasty or arthrodesis (if bone stock poor)

Type I (swan-neck with MCP flexion deformity) is the most common pattern requiring MCP arthroplasty.

Post-Traumatic Arthritis Mechanism

Direct Cartilage Injury:

  • Intra-articular fracture of metacarpal head or proximal phalanx base
  • Articular step-off greater than 2mm leads to abnormal load distribution
  • Focal cartilage loss at impact site
  • Secondary degenerative changes over months to years

Chronic Instability:

  • Collateral ligament injury (acute or chronic)
  • Recurrent MCP subluxation/dislocation
  • Abnormal joint kinematics cause cartilage wear
  • Progressive arthrosis

Stiffness-Related:

  • Prolonged immobilization after MCP injury
  • Adhesions and capsular contracture
  • Decreased joint motion leads to cartilage nutrition impairment
  • Degenerative changes from stiffness

Primary Osteoarthritis (Rare)

Mechanism:

  • Idiopathic cartilage degeneration
  • Repetitive microtrauma in manual laborers
  • Genetic predisposition (rare in MCPs compared to DIP/PIP/CMC-1)
  • Progressive: cartilage loss, subchondral sclerosis, osteophyte formation

Why rare at MCP?

  • MCP joint is congruous and mobile (less focal stress compared to DIP/PIP)
  • CMC-1 (thumb base) is much more common site for primary OA

Clinical Presentation and Assessment

History

Rheumatoid Arthritis:

  • Bilateral symmetric hand pain and stiffness
  • Morning stiffness greater than 1 hour (classic, improves with activity)
  • Progressive ulnar drift and visible deformity
  • Difficulty with power grip (holding objects) and precision pinch
  • Known RA diagnosis with systemic involvement (other joints, lungs, heart)
  • DMARD treatment history (methotrexate, biologics)
  • Duration of hand symptoms (months to years)

Post-Traumatic:

  • History of MCP trauma (fracture, dislocation, ligament injury)
  • Unilateral, single digit pain and stiffness
  • Reduced ROM compared to contralateral side
  • Pain with gripping activities
  • Delayed onset (months to years after injury)

Primary OA:

  • Insidious onset, gradual progression
  • Usually older age (greater than 60 years)
  • Occupational history (manual labor, repetitive gripping)
  • Less systemic symptoms than RA

Examination

Inspection:

  • Ulnar drift: Fingers deviate ulnarly at MCPs (pathognomonic for rheumatoid)
  • Volar subluxation: Proximal phalanx displaced volarly, dorsal step-off at MCP
  • Swelling: Boggy synovitis at MCP joints (active RA), fusiform swelling
  • Deformity: Swan-neck (MCP flexion, PIP hyperextension, DIP flexion) or boutonniere at IP joints
  • Extensor tendon position: Displaced ulnarly into valleys between MCP heads
  • Skin: Rheumatoid nodules (extensor surface, olecranon, MCP), thinning, fragility
  • Z-collapse: Wrist radial deviation with MCP ulnar drift

Palpation:

  • MCP joint line tenderness (dorsal palpation)
  • Synovial thickening (boggy, compressible, warm in active inflammation)
  • Collateral ligament stability (radial and ulnar stress testing at MCP)
  • Volar plate (test for hyperextension laxity)

Range of Motion:

  • Active MCP flexion-extension: Normal 0-90 degrees, reduced in arthritis
  • Passive ROM: Compare to active (capsular tightness vs extensor lag)
  • Extensor lag: Inability to fully extend MCP actively (extensor displacement/weakness)
  • Compare to contralateral hand

Special Tests:

  • Intrinsic tightness test: With MCP extended, attempt PIP flexion. If intrinsics tight, PIP flexion is limited. With MCP flexed (relaxes intrinsics), PIP flexion should improve.
  • Extensor lag: Active extension deficit compared to passive extension (indicates extensor tendon pathology)
  • Collateral ligament stability: Radial and ulnar stress at MCP in flexion (normally tight) and extension (normally lax). Excessive laxity suggests ligament attenuation.
  • Grip strength: Dynamometer testing (compare to contralateral, age-matched norms)
  • Pinch strength: Key pinch and pulp pinch (assess thumb MCP stability)

Functional Assessment:

  • Power grip: Holding objects, jar opening
  • Precision pinch: Writing, buttoning
  • ADLs: Dressing, eating, hygiene
  • Work demands: Manual labor vs sedentary

Examination findings guide surgical planning and inform patient expectations.

Radiographic Assessment

Standard Views:

  • PA (posteroanterior) hand x-ray: Evaluate joint space, erosions, ulnar drift
  • Lateral hand x-ray: Assess volar subluxation of proximal phalanx
  • Oblique views: Additional detail of MCP joint surfaces
  • Bilateral hands: Compare symmetry (rheumatoid is bilateral and symmetric)

Rheumatoid Arthritis Radiographic Progression

Early Findings:

  • Periarticular osteopenia (juxta-articular bone loss)
  • Soft tissue swelling (fusiform MCP)
  • Maintained joint space initially
  • No erosions yet

Moderate Findings:

  • Joint space narrowing (less than 50% loss)
  • Marginal erosions at MCP (bare areas not covered by cartilage)
  • Subchondral cysts
  • Volar subluxation of proximal phalanx (lateral view)
  • Ulnar deviation (PA view)

Late Findings:

  • Severe joint space narrowing (greater than 50% loss or complete loss)
  • Large erosions (central and marginal)
  • Volar and ulnar subluxation
  • Metacarpal head destruction
  • Ankylosis (rare, usually fibrous)
  • Mutilating arthropathy (opera glass hand, telescoping digits)

Larsen Radiographic Grading (Rheumatoid MCP)

GradeRadiographic FindingsManagement Implication
0NormalNo surgical indication
IPeriarticular soft tissue swelling, osteopenia, no erosionsNon-operative (DMARDs, splinting)
IIOne or more erosions, joint space narrowing less than 50%Consider synovectomy (rarely done now), continue medical management
IIIErosions, joint space narrowing greater than 50%, mild subluxationSurgical candidate (arthroplasty or arthrodesis)
IVSevere erosions, marked subluxation, bone deformityStrong surgical indication
VMutilating deformity, complete joint destruction, ankylosisArthroplasty (if bone stock adequate) or arthrodesis

Grade III-V typically require surgical intervention if symptomatic and failed medical management.

Post-Traumatic OA Findings

  • Joint space narrowing (usually focal, asymmetric)
  • Subchondral sclerosis (increased bone density)
  • Subchondral cysts
  • Osteophyte formation (dorsal MCP prominence)
  • Post-traumatic deformity (malunion, articular step-off)
  • Usually unilateral, single digit

Advanced Imaging (Rarely Needed)

MRI:

  • Indications: Assess synovitis extent, erosions not visible on x-ray, tendon integrity, rule out occult fracture
  • Findings: Synovial enhancement (active inflammation), erosions (T1 dark, bone destruction), marrow edema (T2 bright, pre-erosive changes), tendon rupture or displacement
  • Not routine: Plain x-rays sufficient for most cases

Ultrasound:

  • Indications: Assess synovial thickening, power Doppler for active inflammation (guide injection or medical therapy)
  • Advantages: Dynamic assessment, real-time, lower cost than MRI
  • Findings: Synovial hypertrophy, joint effusion, power Doppler signal (active synovitis), erosions
  • Use: Rheumatology follow-up, not routine orthopaedic assessment

Plain radiographs are the primary imaging modality for diagnosis and surgical planning.

Laboratory Tests

Rheumatoid Arthritis Workup:

  • Rheumatoid factor (RF): Positive in 70-80% of RA patients (IgM antibody against Fc portion of IgG)
    • Not specific: Can be positive in other conditions (hepatitis C, cryoglobulinemia, elderly)
  • Anti-CCP (anti-cyclic citrullinated peptide) antibodies: Positive in 70% of RA, more specific than RF
    • High specificity (greater than 95%) for RA
    • Prognostic: Predicts erosive disease
  • ESR (erythrocyte sedimentation rate): Elevated in active inflammation (guides DMARD therapy)
  • CRP (C-reactive protein): More specific than ESR for acute inflammation, tracks disease activity
  • ANA (antinuclear antibody): May be positive in RA (20-30%), consider overlap syndromes (SLE, Sjogren)
  • CBC: Anemia of chronic disease (normocytic, normochromic), thrombocytosis (active inflammation)

Seronegative Spondyloarthropathies:

  • RF and anti-CCP: Negative (hence "seronegative")
  • HLA-B27: Positive in ankylosing spondylitis (90%), reactive arthritis (60-80%), psoriatic arthritis (20%)
  • ESR/CRP: May be elevated
  • Clinical diagnosis: Psoriasis (skin, nail changes), axial involvement, DIP joint arthritis

Psoriatic Arthritis:

  • RF negative, anti-CCP negative
  • May have elevated ESR/CRP
  • Diagnosis: Clinical (psoriasis, nail pitting, oil spots, DIP and MCP involvement, sausage digits)
  • X-ray: "Pencil-in-cup" deformity at DIP, erosions, osteolysis

Crystalline Arthropathy (Gout, Pseudogout):

  • Serum uric acid: Elevated in gout (greater than 6.8 mg/dL), but may be normal during acute attack
  • Joint aspiration (arthrocentesis):
    • Gout: Negatively birefringent needle-shaped monosodium urate crystals (yellow when parallel to polarizer)
    • Pseudogout: Positively birefringent rhomboid-shaped calcium pyrophosphate crystals (blue when parallel)
    • Synovial fluid: Inflammatory (WBC greater than 2000, often greater than 50,000 in acute)
  • X-ray: Chondrocalcinosis (pseudogout, CPPD), tophi (gout, soft tissue masses)

Pre-operative Labs (if surgery planned):

  • CBC, CMP (comprehensive metabolic panel): Baseline
  • ESR/CRP: Assess disease activity (defer surgery if active flare)
  • Nutrition: Albumin, prealbumin (wound healing)
  • Coordination with rheumatology: DMARD perioperative management (methotrexate often held 1-2 weeks pre-op, biologics held per half-life)

Laboratory tests confirm diagnosis and guide medical management, but imaging and clinical examination determine surgical candidacy.

Non-Operative Management

📊 Management Algorithm
Management algorithm for Mcp Joint Arthritis
Click to expand
Management algorithm for Mcp Joint ArthritisCredit: OrthoVellum

Conservative Treatment Goals:

  • Reduce inflammation and pain
  • Preserve function and ROM
  • Slow disease progression (rheumatoid)
  • Delay or avoid surgery
  • Optimize medical management before considering surgical intervention

Disease-Modifying Therapy (Rheumatoid)

DMARDs (Disease-Modifying Anti-Rheumatic Drugs):

First-Line:

  • Methotrexate (MTX): 10-25mg weekly (oral or subcutaneous)
    • Mechanism: Folate antagonist, anti-inflammatory
    • Efficacy: 60-70% response rate
    • Monitoring: CBC, LFTs, renal function (every 8-12 weeks)
    • Side effects: Nausea, hepatotoxicity, bone marrow suppression, teratogenic
    • Supplement: Folic acid 1mg daily (reduces side effects)

Alternative/Combination:

  • Sulfasalazine: 2-3g daily (divided doses)
    • Efficacy: Moderate (less than MTX)
    • Use: Combination with MTX or if MTX intolerant
  • Hydroxychloroquine: 200-400mg daily
    • Efficacy: Mild disease
    • Monitoring: Ophthalmology (retinal toxicity, rare)
  • Leflunomide: 10-20mg daily
    • Efficacy: Similar to MTX
    • Use: MTX alternative

Triple Therapy: MTX + sulfasalazine + hydroxychloroquine (moderate-severe RA, as effective as some biologics)

Biologic DMARDs (Moderate-Severe RA)

Anti-TNF Agents:

  • Adalimumab (Humira): 40mg subcutaneous every 2 weeks
  • Etanercept (Enbrel): 50mg subcutaneous weekly
  • Infliximab (Remicade): 3-10mg/kg IV every 8 weeks (with MTX)
  • Mechanism: Inhibit TNF-alpha (key inflammatory cytokine)
  • Efficacy: 60-70% ACR20 response (20% improvement)
  • Risks: Infections (TB reactivation, screen PPD), malignancy (lymphoma, skin cancer)

IL-6 Inhibitors:

  • Tocilizumab (Actemra): 8mg/kg IV every 4 weeks or 162mg subcutaneous weekly
  • Sarilumab (Kevzara): 200mg subcutaneous every 2 weeks
  • Mechanism: Block IL-6 receptor
  • Efficacy: Similar to anti-TNF

JAK Inhibitors (Newer):

  • Tofacitinib (Xeljanz): 5mg oral twice daily
  • Baricitinib (Olumiant): 2mg oral daily
  • Mechanism: Inhibit Janus kinase (intracellular signaling)
  • Efficacy: Similar to biologics, oral administration (advantage)
  • Risks: Infections, thrombosis (black box warning)

B-Cell Depletion:

  • Rituximab (Rituxan): 1000mg IV x2 (day 0 and 14), repeat every 6 months
  • Mechanism: Depletes CD20+ B cells
  • Use: Failed anti-TNF

T-Cell Costimulation Blockade:

  • Abatacept (Orencia): IV or subcutaneous
  • Mechanism: Blocks T-cell activation

Indication for Biologics: Moderate-severe RA uncontrolled on MTX monotherapy, high disease activity, erosive disease.

Perioperative Management: Hold anti-TNF for 1-2 half-lives pre-op (e.g., adalimumab hold 2-4 weeks), restart when wound healed (2 weeks post-op). Coordinate with rheumatology.

Anti-Inflammatory Medications

NSAIDs:

  • Ibuprofen: 400-800mg three times daily
  • Naproxen: 500mg twice daily
  • Celecoxib (COX-2 selective): 200mg daily or twice daily
  • Mechanism: Inhibit cyclooxygenase, reduce prostaglandin synthesis
  • Efficacy: Symptomatic relief (pain, stiffness), do NOT modify disease progression
  • Risks: GI bleeding (PPI co-prescription if high risk), renal impairment, cardiovascular events (especially COX-2 inhibitors)
  • Monitoring: Renal function, CBC

Corticosteroids:

  • Low-dose oral prednisone: 5-10mg daily
    • Use: Acute flares, bridge therapy while starting DMARDs (takes 8-12 weeks for DMARD effect)
    • Minimize long-term use: Osteoporosis, infection risk, glucose intolerance, Cushing syndrome
    • Taper: Gradual taper when DMARDs effective
  • Intra-articular corticosteroid injections: See next tab

Medical management is first-line for rheumatoid MCP arthritis. Surgery reserved for failed medical management with persistent symptoms and functional impairment.

Corticosteroid Injections

Indications:

  • Active synovitis with pain and swelling
  • MCP joint effusion
  • Failed oral medications (NSAIDs, DMARDs optimized)
  • Temporary relief while awaiting DMARD effect
  • Patient refuses or cannot tolerate surgery

Technique:

  • Approach: Dorsal, between extensor tendon and collateral ligament
  • Needle: 25-27 gauge, 1 inch
  • Medication:
    • Triamcinolone acetonide: 20mg (0.5-1ml)
    • Methylprednisolone: 20-40mg (0.5-1ml)
    • Betamethasone: 3-6mg
  • Local anesthetic: Optional (lidocaine 1%, 0.5ml) to confirm intra-articular placement (immediate pain relief)
  • Sterile technique: Alcohol prep, no-touch technique

Post-Injection:

  • Rest hand for 24-48 hours
  • Ice for 15 minutes (reduce post-injection flare)
  • Avoid heavy gripping for 1 week

Efficacy:

  • Pain relief: 50-70% of patients
  • Duration: 3-6 months (less than larger joints like knee)
  • Less effective in small joints compared to knee, shoulder

Risks:

  • Cartilage damage: Limit to 3 injections per year, avoid frequent injections
  • Tendon weakening/rupture: Avoid injecting into extensor tendon
  • Infection: Rare (less than 1 in 10,000), strict aseptic technique
  • Subcutaneous atrophy: Fat atrophy, skin depigmentation (improper technique, superficial injection)
  • Hyperglycemia: Diabetic patients (monitor glucose)

Contraindications:

  • Active infection
  • Overlying cellulitis
  • Coagulopathy (relative)

Splinting

MCP Ulnar Drift Orthosis:

  • Design: Custom-molded thermoplastic or prefabricated splint
  • Function: Holds MCPs in neutral alignment (0 degrees radial-ulnar deviation)
  • Wear schedule: During activities (gripping, writing) or at night
  • Efficacy: Does NOT reverse deformity, only slows progression
  • Duration: Long-term use (years)

Resting Hand Splint:

  • Design: Full hand splint
  • Position: Wrist 20-30 degrees extension, MCPs 30-45 degrees flexion, IPs extended (intrinsic plus position)
  • Indication: Acute rheumatoid flares (painful synovitis)
  • Function: Reduces pain, prevents deformity during inflammation
  • Wear: Night splinting during flares, remove during day for function

Dynamic Extension Splint:

  • Use: Post-operative (after silicone arthroplasty)
  • Design: Outrigger with elastic bands pulling MCPs into extension and radial deviation
  • Function: Maintains MCP extension, prevents ulnar drift recurrence
  • Critical: 6 weeks full-time, then night splinting for 3 months

Splinting is adjunctive, not curative. Primary management is medical (DMARDs, biologics).

Occupational Therapy and Hand Therapy

Goals:

  • Preserve ROM and strength
  • Protect joints from deforming forces
  • Improve function with ADLs
  • Educate patient on joint protection

Joint Protection Education:

  • Avoid ulnar-deviating forces: Use jar openers, twist with radial deviation (not ulnar)
  • Use larger joints: Carry bags on forearm (not fingers), push doors with body (not hand)
  • Reduce grip force: Use built-up utensils (larger diameter reduces grip force), adaptive equipment
  • Rest during flares: Avoid heavy activities during active synovitis
  • Proper ergonomics: Workstation setup, keyboard/mouse positioning

ROM Exercises:

  • Active MCP flexion-extension: Fist making, finger extension exercises (maintain ROM)
  • Passive ROM: Gentle passive stretching (therapist or self)
  • Frequency: Daily, multiple sessions (10 reps each)
  • Avoid aggressive stretching: Can worsen inflammation

Strengthening:

  • Gentle grip strengthening: Therapy putty (soft to medium resistance), foam ball squeezes
  • Avoid heavy resistance in active disease (worsens synovitis)
  • Progression: Once inflammation controlled (DMARD effect), gradually increase resistance

Adaptive Equipment:

  • Built-up utensils: Larger diameter handles (forks, spoons, pens)
  • Key turners: Leverage devices for key turning (avoid ulnar deviation)
  • Jar openers: Reduce grip force
  • Button hooks, zipper pulls: Assistive dressing devices
  • Electric can openers: Reduce repetitive gripping

Splinting: As above (MCP ulnar drift orthosis, resting splints)

Functional Training:

  • ADL practice: Dressing, eating, hygiene with adaptive equipment
  • Work simulation: Task-specific training
  • Energy conservation: Pacing, rest breaks

Hand therapy is essential non-operative management and critical post-operative for arthroplasty success (dynamic splinting).

Non-operative management should be optimized for 3-6 months before considering surgery.

Indications for Surgical Management:

  • Failed conservative management (DMARD/biologic therapy, injections, splinting) for at least 3-6 months
  • Persistent pain affecting ADLs and quality of life
  • Progressive deformity affecting function (ulnar drift limiting grip, volar subluxation)
  • Severe ulnar drift or volar subluxation (cosmetic and functional concerns)
  • Extensor tendon rupture or displacement (mechanical dysfunction)
  • Patient desire for improved alignment and function
  • Larsen Grade III-V radiographic changes (severe erosions, subluxation)

Surgical Management

Silicone MCP Arthroplasty

Historical Context:

  • Introduced by Alfred Swanson in 1960s-1970s
  • Revolutionized rheumatoid hand surgery
  • Flexible spacer concept (not load-bearing hinge)
  • Fibrous encapsulation provides stability

Indications:

  • Rheumatoid MCP arthritis with ulnar drift and/or volar subluxation
  • Post-traumatic MCP arthritis (digits 2-5)
  • Failed conservative management (DMARDs, splinting, injections for greater than 3-6 months)
  • Desire to preserve motion (vs arthrodesis)
  • Larsen Grade III-V radiographic changes
  • Functional impairment (difficulty with grip, ADLs)

Contraindications:

  • Active infection (absolute)
  • Inadequate soft tissue coverage (exposed bone, compromised skin)
  • Severe bone loss (insufficient bone stock for implant stems)
  • Thumb MCP (arthrodesis preferred)
  • Active rheumatoid flare (defer until controlled)
  • Non-compliant patient (will not adhere to post-op splinting protocol)

Implant Types:

  • Swanson silicone implant: Original design, hinge with stems
  • Sutter silicone implant: Similar to Swanson
  • NeuFlex: Newer silicone design with titanium grommets (reinforced)
  • Pyrocarbon (surface replacement): Not silicone, requires intact bone stock, higher revision rate, NOT standard
  • Silicone is standard: Flexible elastomer, NOT load-bearing, acts as spacer

Silicone Implant Mechanism:

  • NOT a true joint replacement: Does not replicate normal joint biomechanics
  • Acts as flexible spacer maintaining joint space
  • Fibrous capsule forms around implant (encapsulation) - provides stability
  • Allows motion through implant flexion (elastomer property)
  • Not load-bearing: Cannot withstand high compressive loads (hence thumb MCP contraindication)

Surgical Technique

Pre-operative Planning:

  • Bilateral hand x-rays (PA, lateral, oblique)
  • Assess bone stock (degree of erosion, metacarpal head destruction)
  • Measure implant size from x-ray (templating)
  • Coordinate with rheumatology (DMARD perioperative management)
  • Optimize medical management (control active synovitis)
  • Educate patient on post-op splinting commitment (6 weeks full-time)

Patient Position:

  • Supine, arm on radiolucent hand table
  • Pneumatic tourniquet (upper arm, 250mmHg)
  • Exsanguination with Esmarch or elevation

Incision:

  • Longitudinal dorsal incision centered over MCP joint
  • 3-4cm length
  • Multiple MCPs: Can use single longitudinal incision (index through small) or separate incisions for each digit
  • Avoid excessive skin undermining (preserve venous drainage)

Exposure:

  1. Subcutaneous dissection: Preserve dorsal veins and cutaneous nerves
  2. Identify extensor tendon: Extensor digitorum communis (EDC) overlying MCP
  3. Develop plane between extensor and joint capsule
  4. Elevate extensor mechanism radially: Preserves sagittal bands if intact, or elevate as a flap if ruptured
  5. Longitudinal capsulotomy: Open capsule to expose MCP joint

Synovectomy (if rheumatoid):

  • Complete synovectomy: Remove all hypertrophic, inflamed synovium from MCP joint
  • Use rongeur, curette, or electrocautery
  • Critical to remove as much pannus as possible (reduces recurrent synovitis)

Bone Preparation:

  1. Resect metacarpal head: Oscillating saw, perpendicular cut to metacarpal shaft
    • Amount: Resect minimal bone (approximately 5-10mm), preserve length
    • Angle: Perpendicular to shaft (not angled)
    • Remove osteophytes, smooth edges
  2. Ream intramedullary canals:
    • Metacarpal canal (hand reamers or burr)
    • Proximal phalanx canal
    • Goal: Snug fit for implant stems (avoid over-reaming)
  3. Trial implant sizing: Insert trial implant, assess fit (should be snug, not loose)
  4. Select definitive implant size: Match to trial size
  5. Insert silicone implant: Stems into metacarpal and proximal phalanx canals
    • Avoid over-stuffing: Too large implant causes stiffness, implant fracture
    • Avoid under-sizing: Too small implant allows recurrent deformity

Soft Tissue Balancing (CRITICAL):

1. Extensor Tendon Centralization:

  • Rationale: Extensor tendon has displaced ulnarly into valley, acts as ulnar deviator
  • Technique: Reposition extensor tendon over center of MCP
  • Suture to radial capsule: 3-0 non-absorbable suture (Ethibond, Ti-Cron), secure extensor to radial side
  • Alternative: Radial sagittal band reconstruction (if sagittal band ruptured)

2. Radial Collateral Ligament Reconstruction:

  • Rationale: Radial collateral ligament is stretched/incompetent, allows ulnar drift
  • Technique: Reef (plicate) radial collateral ligament, or
  • Reconstruct: Use radial capsule, suture to metacarpal neck (radial side)
  • Goal: Tighten radial structures, resist ulnar drift

3. Intrinsic Release (if tight):

  • Test intrinsic tightness: With MCP extended, attempt PIP flexion (limited if intrinsics tight)
  • Release ulnar intrinsics: Release ulnar interosseous from proximal phalanx (ulnar side)
  • Preservation: Preserve radial intrinsics (counteract ulnar drift)

4. Crossed Intrinsic Transfer (advanced, selective):

  • Indication: Severe recurrent ulnar drift despite ligament reconstruction
  • Technique: Transfer ulnar intrinsic to radial side (e.g., transfer ulnar lateral band to radial side)
  • Rarely performed: Reserve for severe, recurrent cases

Without soft tissue balancing, arthroplasty WILL fail (recurrent ulnar drift).

Closure:

  • Capsule: Close capsule over implant (2-0 absorbable suture, Vicryl)
  • Extensor mechanism: Ensure extensor centralized, close sagittal bands if opened
  • Subcutaneous: 3-0 absorbable
  • Skin: 4-0 or 5-0 nylon, running or interrupted

Dressing:

  • Non-adherent dressing (Xeroform), gauze
  • Immediate application of dynamic MCP extension splint (see post-op protocol)

Post-operative Protocol

Immobilization:

  • Dynamic MCP extension outrigger splint:
    • Custom-fabricated by certified hand therapist
    • Wrist in 20-30 degrees extension, MCPs in extension (0 degrees) with radial deviation
    • Elastic bands pull MCPs into extension and radial deviation
    • Allows controlled passive flexion, blocks ulnar deviation
  • Wear schedule:
    • Weeks 0-6: Full-time (23 hours/day, remove for hygiene only)
    • Weeks 6-12: Night-time only
    • Months 3-6: Night-time as needed

Rehabilitation:

  • Immediate (Day 1-2): Passive ROM with dynamic splint (flexion allowed, extension assisted by splint)
  • Week 1: Hand therapy begins, passive ROM exercises (therapist-guided)
  • Weeks 2-6: Progressive passive ROM, gentle active ROM within splint
  • Week 6: Remove dynamic splint during day, begin active ROM exercises
  • Weeks 6-12: Progressive active ROM, strengthening begins (gentle resistance)
  • Week 12: Progress to full strengthening (power grip, resistance training)

Critical: Patient compliance with dynamic splinting is key to preventing recurrent ulnar drift.

Outcomes

Range of Motion:

  • Expected: 30-40 degrees MCP flexion arc (0-40 degrees typical)
  • Not normal: Silicone does not restore full ROM (normal 0-90 degrees)
  • Functional: 30-40 degrees sufficient for most ADLs and grip

Alignment:

  • Ulnar drift correction: 80-85% maintain correction long-term (if soft tissue balanced)
  • Volar subluxation correction: 85-90% maintain reduction

Pain Relief:

  • Significant improvement: 80-90% of patients
  • Mechanism: Removes painful synovium, stabilizes joint, improves alignment

Survivorship:

  • 10 years: 80-90% survival (implant in situ, functioning)
  • 15 years: 60-70% survival
  • Failure modes: Implant fracture (5-10%), subsidence (5%), recurrent deformity (10-15%)

Patient Satisfaction:

  • High: 85-90% satisfied with pain relief and alignment
  • Expectations: Counsel that this is spacer, not normal joint (limited ROM)

Complications:

  • Implant fracture: 5-10% (see Complications section)
  • Recurrent ulnar drift: 10-15% (inadequate soft tissue balancing)
  • Stiffness: 20-30% (less than expected ROM, adhesions)
  • Subsidence: 5% (implant sinks into bone)
  • Infection: Less than 2%
  • Squeaking: Occasional patient complaint (silicone friction)

Silicone MCP arthroplasty is highly successful for rheumatoid MCP arthritis when combined with meticulous soft tissue balancing and post-operative dynamic splinting.

MCP Joint Arthrodesis (Fusion)

Indications:

  • Thumb MCP arthritis (post-traumatic or rheumatoid) - PREFERRED over arthroplasty
  • Post-traumatic arthritis with significant bone loss (insufficient bone stock for arthroplasty)
  • Failed MCP arthroplasty (implant fracture, subsidence, infection)
  • Young, high-demand patients (manual labor, high grip forces)
  • Severe MCP instability (collateral ligament incompetence)
  • Patient preference for stability over motion

Contraindications:

  • Stiff IP joints (if IP joints fused or stiff, need MCP motion to compensate)
  • Bilateral multiple digit fusion (would eliminate all grip function)
  • Index-small fingers in low-demand patients (arthroplasty preferred)

Rationale for Thumb MCP Arthrodesis:

  • Thumb MCP requires stability for pinch (lateral key pinch, pulp pinch)
  • High loads during pinch (5-10x pinch force)
  • Arthroplasty risks instability, recurrent pain, implant failure
  • Fusion provides pain-free stable pinch - gold standard for thumb MCP

Fusion Position (CRITICAL)

Cascading Flexion Principle:

  • Ulnar digits progressively more flexed (mimics normal hand cascade)
  • Allows all digits to contact palm during grip
DigitMCP Fusion AngleRationale
Thumb10-15 degrees flexion, neutral rotationStable key pinch and pulp pinch position
Index25-30 degrees flexionPrecision grip, pointing
Middle35-40 degrees flexionPower grip, central digit
Ring40-45 degrees flexionPower grip, more ulnar
Small45-50 degrees flexionMost flexion, ulnar border

Rotation: Neutral (digit points toward scaphoid when flexed)

Confirm intraoperatively: Test pinch (thumb) or grip (digits 2-5) with trial position before fixation.

Surgical Technique (Thumb MCP Arthrodesis)

Patient Position:

  • Supine, arm on hand table
  • Tourniquet (upper arm, 250mmHg)

Incision:

  • Dorsal longitudinal over thumb MCP joint
  • 3-4cm length
  • Centered over MCP joint line

Exposure:

  1. Subcutaneous dissection, preserve dorsal veins
  2. Identify EPL tendon (radial to incision)
  3. Protect EPL: Retract radially
  4. Open joint capsule longitudinally (ulnar side of EPL)
  5. Expose MCP joint

Synovectomy (if rheumatoid):

  • Complete synovectomy if synovitis present

Joint Preparation:

  1. Resect articular cartilage:
    • Metacarpal head: Saw or rongeur, remove cartilage down to subchondral bone
    • Proximal phalanx base: Remove cartilage
  2. Shape surfaces:
    • Cup-and-cone: Metacarpal head conical, phalanx base concave (maximize contact)
    • OR Flat cuts: Perpendicular cuts on both surfaces (simpler, adequate contact)
  3. Decortication: Burr or curette to create bleeding bone (promotes fusion)
  4. Trial position:
    • Flex thumb MCP 10-15 degrees
    • Neutral rotation (thumb pad faces radially)
    • Test pinch: Simulate key pinch and pulp pinch (confirm good position)
  5. Provisional fixation: K-wires (0.045 or 0.062 inch, 2-3 wires crossed)

Definitive Fixation Options:

1. Plate and Screws (Preferred):

  • Dorsal locking plate: 2.0mm or 2.4mm hand plate
  • Screws: 2-3 screws in metacarpal, 2-3 in proximal phalanx
  • Advantage: Rigid fixation, allows earlier mobilization, higher fusion rate
  • Technique: Apply plate dorsally, compress joint if possible, lock screws

2. K-wires (Alternative):

  • Two or three crossed K-wires: 0.045 or 0.062 inch
  • Configuration: Oblique wires crossing fusion site
  • Advantage: Simple, low profile
  • Disadvantage: Less rigid, requires longer immobilization (6 weeks), wire removal needed

3. Headless Compression Screw:

  • Single screw (e.g., Herbert screw, Acutrak screw) across fusion site
  • Technique: Lag screw from metacarpal head into proximal phalanx
  • Advantage: Low profile, compression, no hardware removal
  • Disadvantage: Requires good bone quality

4. Tension Band Wiring (Rare):

  • Figure-of-8 wire dorsally with K-wires
  • Rarely used for MCP fusion

Plate fixation is preferred (most rigid, highest fusion rate, allows earlier ROM of IP joint).

Bone Grafting:

  • Usually NOT needed if good bone contact
  • Indications: Significant bone loss, poor bone quality, revision fusion
  • Source: Iliac crest (cancellous), distal radius (local)

Closure:

  • Capsule (2-0 absorbable)
  • Subcutaneous (3-0 absorbable)
  • Skin (4-0 or 5-0 nylon)

Dressing:

  • Non-adherent, gauze
  • Thumb spica splint (immobilizes wrist, thumb MCP, allows thumb IP motion)

Post-operative Protocol

Immobilization:

  • If plate fixation: Thumb spica splint 2 weeks (protective), then removable splint, allow thumb IP ROM
  • If K-wire fixation: Thumb spica cast 6 weeks (rigid immobilization until fusion), then remove K-wires

Rehabilitation:

  • Weeks 0-2 (plate) or 0-6 (K-wires): Immobilization, no ROM
  • Week 2 (plate): Begin thumb IP ROM, keep MCP immobilized in removable splint
  • Week 6: X-ray to assess fusion
    • If fusing: Discontinue splint, progressive ROM and strengthening
    • If not fusing: Continue immobilization 2-4 more weeks, repeat x-ray
  • Week 8-12: Progressive strengthening (grip, pinch)

Outcomes

Fusion Rate:

  • 90-95% union rate (plate fixation)
  • Time to fusion: 8-12 weeks radiographically
  • Nonunion: 5-10% (risk factors: smoking, poor bone quality, rheumatoid)

Pain Relief:

  • Excellent: 95%+ near-complete pain relief
  • Mechanism: Eliminates painful arthritic joint motion

Function:

  • Stable pinch: Key advantage (lateral key pinch, pulp pinch)
  • Loss of MCP motion: Accept for stability (IP joint compensates)
  • Grip strength: Preserved or improved (stable thumb post)

Patient Satisfaction:

  • High: 90%+ satisfaction for thumb MCP fusion
  • Preferred over arthroplasty for thumb

Complications:

  • Nonunion: 5-10% (see below)
  • Malposition: Fused in wrong angle (too much/little flexion, rotation) - avoid by testing intraoperatively
  • Hardware prominence: Plate or screw prominence dorsally (rare, remove if symptomatic)
  • Infection: Less than 2%
  • Stiffness of IP joint: Secondary stiffness (hand therapy)

Thumb MCP arthrodesis is the gold standard for thumb MCP arthritis, providing pain-free stable pinch.

MCP Synovectomy

Historical Context:

  • Performed in pre-DMARD era for rheumatoid MCP synovitis
  • Goal: Remove inflamed synovium, prevent joint destruction
  • Largely supplanted by DMARDs/biologics (medical management more effective systemically)

Indication (Rare):

  • Early rheumatoid MCP arthritis (Larsen Grade I-II) with persistent synovitis DESPITE optimized DMARD therapy
  • BEFORE significant erosions or deformity
  • Isolated MCP synovitis (not systemic flare)

Contraindication:

  • Larsen Grade III-V (significant erosions, deformity) - need arthroplasty/arthrodesis, not synovectomy
  • Active systemic rheumatoid flare (optimize medical management)
  • Poor medical optimization (DMARD not tried or insufficient duration)

Surgical Technique:

  • Dorsal approach to MCP (as for arthroplasty)
  • Open capsule longitudinally
  • Complete synovectomy: Remove all hypertrophic, inflamed synovium with rongeur, curette
  • Inspect extensor tendons (centralize if displaced)
  • Repair radial collateral ligament if lax
  • Close capsule, skin

Adjunct Procedures (Combine with Synovectomy):

  • Extensor tendon centralization: If extensor displaced ulnarly
  • Radial collateral ligament repair: If radial laxity present
  • Intrinsic release: If tight ulnar intrinsics

Post-operative:

  • Splint in MCP extension, radial deviation for 2 weeks
  • Then hand therapy (ROM, strengthening)

Outcomes:

  • Temporary relief: 3-5 years average (synovitis recurs)
  • Pain improvement: 70-80% short-term
  • Does NOT reverse deformity, only slows progression
  • Does NOT prevent erosions long-term (synovitis recurs)

Current Role:

  • Very limited: DMARDs/biologics more effective at controlling synovitis systemically
  • Synovectomy occasionally combined with arthroplasty (remove synovium during joint replacement)
  • Rarely performed as isolated procedure

Soft Tissue Adjunct Procedures

These are performed in combination with arthroplasty, not as isolated procedures:

1. Extensor Tendon Centralization:

  • Reposition extensor tendon over MCP center (from ulnar displaced position)
  • Suture to radial capsule or reconstruct radial sagittal band
  • Essential for preventing recurrent ulnar drift after arthroplasty

2. Radial Collateral Ligament Reconstruction:

  • Reef (plicate) stretched radial collateral ligament
  • Suture radial capsule to metacarpal neck (tighten radial structures)
  • Resists ulnar drift forces post-operatively

3. Ulnar Intrinsic Release:

  • Release tight ulnar interosseous muscle from proximal phalanx
  • Indicated if intrinsic tightness test positive
  • Reduces ulnar deviating force

4. Crossed Intrinsic Transfer:

  • Transfer ulnar lateral band to radial side
  • Creates active radial deviation force
  • Rarely performed, reserved for severe recurrent ulnar drift

Critical Point: Arthroplasty without soft tissue balancing has high failure rate (recurrent ulnar drift). Soft tissue procedures are NOT optional.

Synovectomy alone is rarely performed. Soft tissue balancing is integral to arthroplasty success.

Failed MCP Arthroplasty: Revision Options

Causes of Failure:

Failure ModeIncidenceMechanism
Implant fracture5-10%Fatigue failure from cyclic loading (silicone not designed for load-bearing)
Recurrent ulnar drift10-15%Inadequate soft tissue balancing at index surgery
Subsidence5%Implant sinks into bone (poor bone stock, over-reaming)
Stiffness20-30%Adhesions, inadequate hand therapy, patient non-compliance
InfectionLess than 2%Early or late infection
SqueakingVariableSilicone friction (patient dissatisfaction, not mechanical failure)

Presentation:

  • Return of pain (indicates implant fracture, subsidence, or recurrent synovitis)
  • Loss of motion (stiffness from adhesions)
  • Recurrent deformity (ulnar drift, volar subluxation)
  • Palpable implant fracture (crepitus, instability)
  • Swelling, erythema (infection)

Imaging:

  • X-ray (PA, lateral):
    • Implant fracture (visible break in silicone)
    • Subsidence (implant sinking into bone, loss of joint space height)
    • Bone resorption around implant
    • Recurrent ulnar drift, volar subluxation

Management Algorithm:

ScenarioTreatment OptionRationale
Implant fracture, good bone stock, asymptomaticObservationFibrous capsule often maintains stability, no need for revision if pain-free
Implant fracture, symptomatic (pain/instability)Revision arthroplastyRemove fractured implant, insert new silicone implant, address soft tissue
Implant fracture, poor bone stockArthrodesisInsufficient bone for revision arthroplasty stems
Recurrent ulnar drift, intact implantRevision soft tissue balancingMore aggressive extensor centralization, ligament reconstruction, crossed intrinsic transfer
Subsidence, minimal symptomsObservationIf pain-free, do not revise
Subsidence, severe (painful)Revision arthroplasty or arthrodesisDepends on bone stock
InfectionImplant removal, antibiotics, staged fusionRemove implant, IV antibiotics, delayed arthrodesis after infection cleared

Revision Arthroplasty Technique:

  1. Remove fractured implant:

    • Dorsal approach (may be scarred from prior surgery)
    • Identify and remove all implant fragments
    • Curette fibrous capsule (encapsulation)
  2. Assess bone stock:

    • Evaluate metacarpal and phalanx canals (bone resorption from subsidence?)
    • If adequate bone: Proceed with revision arthroplasty
    • If poor bone: Arthrodesis
  3. Insert larger implant if bone loss:

    • If canals enlarged from subsidence, use larger implant size
    • Avoid over-stuffing (causes stiffness)
  4. Aggressive soft tissue balancing (CRITICAL):

    • Extensor tendon centralization (more aggressive than primary)
    • Radial collateral ligament reconstruction (reef radial structures tightly)
    • Release ulnar intrinsics
    • Consider crossed intrinsic transfer (transfer ulnar lateral band to radial side) to actively resist ulnar drift
  5. Post-operative dynamic splinting:

    • Even more critical than primary (6 weeks full-time, then night splinting 6 months)

Outcomes of Revision Arthroplasty:

  • Less predictable than primary surgery
  • Satisfactory outcome: 70-80% (vs 85-90% primary)
  • Higher recurrent deformity rate: 20-30%
  • Counsel realistic expectations

Salvage Arthrodesis:

  • Indication: Failed arthroplasty with poor bone stock, infection, patient preference for stability
  • Technique:
    • Remove implant and all fibrous tissue
    • Prepare metacarpal and phalanx for fusion (as in primary arthrodesis)
    • Bone grafting often needed (iliac crest or distal radius) due to bone loss
    • Plate fixation preferred
  • Fusion position: As per primary arthrodesis (cascading flexion)
  • Outcomes: 80-90% fusion rate, excellent pain relief, loss of motion (accept)

Revision surgery is challenging. Emphasize soft tissue balancing and patient compliance with splinting.

Complications and Their Management

Complications of MCP Arthritis Surgery

ComplicationIncidencePreventionManagement
Implant fracture5-10%Proper implant sizing, avoid over-stuffingObserve if asymptomatic; revise if painful or unstable
Recurrent ulnar drift10-15%Meticulous soft tissue balancing, dynamic splintingRevision with aggressive soft tissue balancing, crossed intrinsic transfer
Stiffness20-30%Early passive motion, intensive hand therapyDynamic splinting, manipulation (rare), tenolysis (if severe adhesions)
InfectionLess than 2%Sterile technique, perioperative antibioticsEarly: Wash out, antibiotics. Late: Implant removal, antibiotics, staged fusion
Subsidence5%Proper implant sizing, avoid over-reamingObserve if mild; revise if severe and symptomatic
Nonunion (arthrodesis)5-10%Rigid fixation (plate), smoking cessation, bone graft if poor qualityRevision fusion with bone graft and plate fixation

Implant Fracture (Silicone Arthroplasty)

Mechanism:

  • Fatigue failure from cyclic loading (silicone is flexible but not indestructible)
  • Occurs over years (typically 5-10 years post-op)
  • Often asymptomatic: Fibrous capsule (encapsulation) maintains some stability even after fracture

Presentation:

  • Many patients asymptomatic (incidental finding on x-ray)
  • Some have return of pain, instability, or crepitus
  • Palpable fracture (rare)

Imaging:

  • X-ray: Visible break in silicone implant (radiolucent line through implant)

Management:

  • If asymptomatic: Observation (no intervention needed)
  • If symptomatic (pain, instability): Revision arthroplasty (remove fractured implant, insert new) OR arthrodesis (if poor bone stock)

Prevention:

  • Proper implant sizing (avoid over-stuffing, which increases stress)
  • Soft tissue balancing (reduces abnormal forces on implant)

Recurrent Ulnar Drift

Mechanism:

  • Inadequate soft tissue balancing at index surgery (extensor not centralized, radial collateral ligament not reconstructed)
  • Patient non-compliance with post-operative dynamic splinting
  • Persistent ulnar intrinsic tightness

Presentation:

  • Progressive ulnar deviation of fingers at MCPs (months to years post-op)
  • Return of pre-operative deformity
  • May be associated with extensor lag

Management:

  • Early (mild): Dynamic extension splinting, hand therapy
  • Established (moderate-severe): Revision surgery with aggressive soft tissue balancing:
    • Extensor tendon centralization (more aggressive suturing to radial capsule)
    • Radial collateral ligament reconstruction (tighten radial structures)
    • Release ulnar intrinsics
    • Crossed intrinsic transfer: Transfer ulnar lateral band to radial side (creates active radial deviation force)

Prevention:

  • Meticulous soft tissue balancing at index surgery (non-negotiable)
  • Post-operative dynamic extension splinting (6 weeks full-time, patient compliance critical)
  • Hand therapy supervision

Stiffness

Mechanism:

  • Adhesions between implant and surrounding tissues
  • Capsular contracture
  • Inadequate hand therapy or patient non-compliance
  • Over-stuffing (implant too large)

Presentation:

  • Limited MCP ROM (less than expected 30-40 degrees)
  • Difficulty with fist making
  • Functional impairment

Management:

  • Primary prevention: Early passive ROM (Day 1-2 post-op), intensive hand therapy
  • Established stiffness:
    • Dynamic splinting (flexion splint to improve flexion, extension splint to improve extension)
    • Gentle manipulation by therapist
    • Manipulation under anesthesia (rare, risk of implant fracture)
    • Tenolysis (surgical release of adhesions, rarely needed)

Prevention:

  • Immediate post-operative passive ROM with dynamic splint
  • Intensive hand therapy (weekly sessions for first 3 months)
  • Patient education and compliance

Infection

Incidence:

  • Less than 2% (rare)

Timing:

  • Early (less than 6 weeks): Surgical site infection
  • Late (greater than 6 weeks): Hematogenous seeding (rare)

Presentation:

  • Pain, swelling, erythema, warmth at MCP
  • Drainage from incision
  • Systemic: Fever, malaise (uncommon)

Diagnosis:

  • Clinical diagnosis
  • Labs: Elevated WBC, ESR, CRP
  • Joint aspiration: Synovial fluid WBC greater than 50,000 (highly suggestive), positive culture
  • X-ray: Usually normal acutely, may show implant loosening if chronic

Management:

  • Early infection (less than 3 weeks, acute):
    • Surgical wash-out (incision and drainage, debridement)
    • Retain implant if well-fixed (attempt salvage)
    • IV antibiotics (6 weeks, culture-directed)
    • Success rate: 50-70% (implant salvage)
  • Late infection or failed salvage:
    • Implant removal (definitive)
    • IV antibiotics (6 weeks)
    • Staged arthrodesis: After infection cleared (3-6 months), perform fusion
  • Prevention:
    • Perioperative antibiotics (cefazolin 1-2g IV within 1 hour of incision)
    • Sterile technique
    • Coordinate DMARD management with rheumatology (hold biologics perioperatively to reduce infection risk)

Infection is rare but devastating (often requires implant removal and fusion).

Outcomes and Evidence

Systematic Review
📚 Chung et al
Key Findings:
  • Silicone MCP arthroplasty: 80-90% survivorship at 10 years
  • Mean ROM: 35 degrees flexion arc (0-35 typical)
  • Significant pain relief in 85% of patients
  • Ulnar drift correction maintained in 80-85%
  • Implant fracture rate 5-10%, often asymptomatic
Clinical Implication: Silicone arthroplasty provides reliable pain relief and alignment correction with good long-term survivorship for rheumatoid MCP arthritis.
Source: J Hand Surg Am 2009

Cohort Study
📚 Goldfarb and Stern
Key Findings:
  • MCP arthrodesis for thumb: 95% fusion rate
  • Excellent pinch stability and pain relief
  • High patient satisfaction (90%+)
  • Preferred over arthroplasty for thumb MCP
  • Fusion position 10-15 degrees optimal for pinch
Clinical Implication: Thumb MCP arthrodesis is superior to arthroplasty for providing stable, pain-free pinch function.
Source: J Bone Joint Surg Am 2003

Classification System
📚 Nalebuff and Millender
Key Findings:
  • Described rheumatoid hand deformity patterns (swan-neck, boutonniere, ulnar drift)
  • Type I (swan-neck) most common pattern
  • Classification guides surgical decision-making
  • Nalebuff classification widely adopted internationally
Clinical Implication: Nalebuff classification is essential framework for understanding and communicating rheumatoid hand pathology.
Source: Clin Orthop Relat Res 1975

Historical Landmark
📚 Swanson
Key Findings:
  • Introduced silicone MCP arthroplasty for rheumatoid arthritis
  • Flexible spacer concept (not load-bearing joint replacement)
  • Fibrous encapsulation provides stability around implant
  • Revolutionized rheumatoid hand surgery
  • Swanson silicone implant remains standard design
Clinical Implication: Swanson's flexible spacer concept remains the gold standard for MCP arthroplasty nearly 50 years later.
Source: J Bone Joint Surg Am 1972

RCT
📚 Delaney et al
Key Findings:
  • Silicone vs surface replacement (pyrocarbon) MCP arthroplasty RCT
  • Similar pain relief and ROM at 5 years follow-up
  • Silicone more cost-effective (lower implant cost)
  • Surface replacement higher revision rate (bone stress shielding)
  • No advantage of surface replacement over silicone
Clinical Implication: Silicone arthroplasty remains gold standard; newer surface replacements are NOT superior and have higher complication rates.
Source: J Hand Surg Eur 2011

Exam Viva Scenarios

Practice these scenarios to excel in your viva examination

VIVA SCENARIOStandard

Scenario 1: Rheumatoid MCP Arthritis

EXAMINER

"A 55-year-old woman with rheumatoid arthritis presents with progressive ulnar drift of all four fingers bilaterally. She has failed DMARD therapy (methotrexate and adalimumab) and has persistent pain with gripping. X-rays show Larsen Grade III changes with volar subluxation and marginal erosions at MCPs. Describe your management."

EXCEPTIONAL ANSWER
This is advanced rheumatoid MCP arthritis with characteristic ulnar drift and volar subluxation. Larsen Grade III indicates severe erosions and joint destruction requiring surgical intervention. Given she has failed optimized medical management (DMARD and biologic therapy) and has functional impairment with pain, she is a candidate for surgical intervention. My recommendation would be silicone MCP arthroplasty for the index through small fingers bilaterally, performed as staged procedures (one hand first, allow recovery 3-6 months, then contralateral hand). The surgical goals are pain relief, correction of ulnar drift, restoration of alignment, and preservation of some motion for grip function. The procedure involves resecting the metacarpal heads with an oscillating saw, reaming the intramedullary canals of both metacarpal and proximal phalanx, and inserting silicone spacer implants with stems into both bones. Critical adjunct procedures that are ESSENTIAL for success include: complete synovectomy to remove inflamed pannus, extensor tendon centralization by repositioning extensors over the MCP center and suturing to radial capsule, radial collateral ligament reconstruction to tighten radial structures and correct ulnar drift, and release of tight ulnar intrinsics if present on examination. Post-operatively, dynamic MCP extension splinting with outrigger for 6 weeks full-time is absolutely critical to maintain alignment and prevent recurrent ulnar drift. Expected outcomes include 30-40 degrees of MCP flexion arc, correction of deformity maintained in 80-85%, significant pain relief in 85%, and 10-15 year implant survivorship. I would counsel about risks including implant fracture (5-10%, often asymptomatic), recurrent deformity (10-15% if soft tissue not balanced), stiffness (20-30%), and the need for hand therapy compliance.
KEY POINTS TO SCORE
Silicone arthroplasty for digits 2-5 (NOT thumb), staged bilaterally
Adjunct soft tissue procedures are ESSENTIAL: synovectomy, extensor centralization, radial collateral ligament reconstruction, intrinsic release
Dynamic MCP extension splinting post-op for 6 weeks full-time (patient compliance critical)
Expected 30-40 degrees ROM, 80-85% maintain alignment, 10-15 year survivorship
COMMON TRAPS
✗Implant alone without soft tissue balancing (will fail with recurrent drift)
✗Not addressing extensor tendon displacement (perpetuates ulnar drift)
✗Offering arthroplasty for thumb MCP (arthrodesis preferred for thumb)
✗Not emphasizing post-operative dynamic splinting (critical for success)
LIKELY FOLLOW-UPS
"Describe the pathomechanics of rheumatoid ulnar drift (VUSEX sequence)"
"What is extensor tendon centralization and why is it critical?"
"What if the thumb MCP is also severely arthritic? (arthrodesis preferred)"
"What are options if arthroplasty fails? (revision arthroplasty vs arthrodesis)"
VIVA SCENARIOStandard

Scenario 2: Thumb MCP Arthritis

EXAMINER

"A 60-year-old man with post-traumatic arthritis of the thumb MCP joint (old intra-articular fracture 10 years ago) has severe pain with lateral key pinch and difficulty with jar opening. He has failed conservative management including NSAIDs, activity modification, and corticosteroid injections. X-rays show joint space loss, subchondral sclerosis, and osteophytes. What is your surgical plan?"

EXCEPTIONAL ANSWER
This is post-traumatic thumb MCP arthritis with functional impairment of pinch, which is a critical function of the thumb for ADLs. For the thumb MCP, my preferred surgical option is arthrodesis rather than arthroplasty. The rationale is that the thumb MCP requires stability for lateral key pinch and pulp pinch, which are high-load activities experiencing forces 5-10 times the pinch force. Arthroplasty with silicone implant risks instability, recurrent pain, and implant failure under these high loads. My surgical plan is thumb MCP arthrodesis fused in 10-15 degrees of flexion with neutral rotation. The procedure involves a dorsal longitudinal incision over the thumb MCP, protecting the EPL tendon radially, opening the joint capsule, and resecting the articular surfaces of the metacarpal head and proximal phalanx base to create either cup-and-cone or flat surfaces for fusion. I would position the thumb in 10-15 degrees of flexion with neutral rotation and critically, I would test this position intraoperatively by simulating key pinch and pulp pinch to confirm this provides good functional position before fixation. For fixation, I prefer a dorsal locking plate with screws as it provides rigid fixation, allows earlier mobilization of the thumb IP joint, and has the highest fusion rate compared to K-wires. Post-operatively, thumb spica splint for 2 weeks for soft tissue healing, then removable splint allowing thumb IP ROM but protecting the fusion site for 6 weeks total. Fusion rate is 90-95% at 8-12 weeks. Outcomes are excellent with near-complete pain relief, stable pinch (key advantage over arthroplasty), and high patient satisfaction (90%+). I would counsel about loss of MCP motion which is accepted for the stability gained.
KEY POINTS TO SCORE
Thumb MCP arthrodesis preferred over arthroplasty (pinch stability requirement)
Fusion position: 10-15 degrees flexion, neutral rotation (TEST intraoperatively with pinch simulation)
Plate fixation preferred over K-wires (more rigid, higher fusion rate, earlier IP mobilization)
95% fusion rate, excellent pain relief, stable pinch, high satisfaction
COMMON TRAPS
✗Offering silicone arthroplasty for thumb MCP (will fail under pinch loads, risks instability)
✗Fusing in hyperextension or excessive flexion (poor functional position)
✗Not testing pinch position intraoperatively before fixation
✗Using K-wires alone without considering plate fixation (less rigid, longer immobilization)
LIKELY FOLLOW-UPS
"What if the patient specifically requests to preserve thumb MCP motion? (counsel against arthroplasty, explain instability risk)"
"What is the fusion position for index MCP if needed? (25-30 degrees flexion)"
"What are alternative fixation options? (K-wires, headless screw, tension band)"
"How do you manage nonunion? (revision fusion with bone graft and rigid plate fixation)"
VIVA SCENARIOChallenging

Scenario 3: Failed MCP Arthroplasty

EXAMINER

"A 58-year-old woman had silicone MCP arthroplasty of the index and middle fingers 8 years ago for rheumatoid arthritis. She now presents with return of pain, recurrent ulnar drift of both digits, and difficulty with grip. X-ray shows fractured silicone implant in the index MCP with some bone resorption around the implant. The middle finger implant is intact but digits have drifted ulnarly. What is your approach to this failed arthroplasty?"

EXCEPTIONAL ANSWER
This patient has a failed silicone MCP arthroplasty with two distinct problems: implant fracture in the index finger and recurrent ulnar drift affecting both digits. Implant fracture occurs in 5-10% of cases, typically from fatigue failure of the silicone elastomer over time. The recurrent ulnar drift suggests inadequate soft tissue balancing at the index procedure. I would first assess her functionally: how much is the pain and deformity affecting her ADLs, grip function, and quality of life? On examination, I would assess the degree of ulnar drift, MCP stability with stress testing, passive and active ROM, and intrinsic tightness. X-rays show the implant fracture in the index MCP, and I would carefully assess bone stock by evaluating for implant subsidence and bone resorption around the implant canals. My options are: 1) Observation if her symptoms are mild and she is low-demand, because the fibrous capsule that forms around the fractured implant (encapsulation) often provides some stability even after fracture, or 2) Revision surgery if she is symptomatic. For revision, if bone stock is adequate on imaging, I would perform revision arthroplasty: remove the fractured implant and all fragments, assess the bone canals for resorption, insert a new silicone implant (possibly larger size if bone canals enlarged from resorption but avoid over-stuffing), and critically, address the soft tissue imbalance more aggressively than the index procedure. This would include meticulous extensor tendon centralization with suturing to radial capsule, radial collateral ligament reconstruction by tightly reefing radial structures, release of ulnar intrinsics, and I would strongly consider a crossed intrinsic transfer (transferring ulnar lateral band to radial side) to create an active radial deviation force to counteract the ulnar drift tendency. Post-operatively, dynamic MCP extension splinting is absolutely essential for 6 weeks full-time, then night splinting for 6 months. If bone stock is poor (significant resorption, thin cortices), arthrodesis is the salvage option with bone grafting from iliac crest or distal radius. I would counsel that revision outcomes are less predictable than primary surgery (70-80% satisfactory outcomes vs 85-90% for primary arthroplasty).
KEY POINTS TO SCORE
Implant fracture: 5-10% incidence, often asymptomatic due to fibrous encapsulation
Recurrent ulnar drift indicates inadequate soft tissue balancing at index surgery
Options: Observation (if asymptomatic) vs revision arthroplasty (if symptomatic and adequate bone stock) vs arthrodesis (if poor bone stock)
Revision requires AGGRESSIVE soft tissue balancing: extensor centralization, ligament reconstruction, intrinsic release, consider crossed intrinsic transfer
COMMON TRAPS
✗Revising with implant exchange alone without addressing soft tissue pathology (will fail again)
✗Not assessing bone stock before planning revision (poor stock requires arthrodesis, not arthroplasty)
✗Offering revision arthroplasty if bone stock is insufficient (need arthrodesis as salvage)
✗Not counseling realistic expectations (revision less predictable than primary surgery)
LIKELY FOLLOW-UPS
"What is crossed intrinsic transfer? (transfer ulnar lateral band to radial side, creates active radial deviation force)"
"When would you choose arthrodesis over revision arthroplasty? (poor bone stock, infection, patient preference for stability, high-demand manual labor)"
"What are all the causes of MCP arthroplasty failure? (implant fracture, recurrent drift, subsidence, infection, stiffness)"
"How do you manage infected MCP arthroplasty? (early: wash-out and antibiotics attempt salvage; late or failed: implant removal, IV antibiotics, staged arthrodesis)"

MCQ Practice Points

Exam Pearl

Q: What is the typical deformity pattern in rheumatoid MCP joint arthritis?

A: Ulnar drift and volar subluxation of the proximal phalanges. Mechanism: Radial collateral ligament attenuation, extensor tendon ulnar subluxation, intrinsic muscle imbalance. Associated with radial deviation at wrist (zig-zag deformity). Sagittal band rupture allows extensor tendon ulnar displacement.

Exam Pearl

Q: What is the preferred surgical treatment for rheumatoid MCP arthritis?

A: Silicone MCP arthroplasty (Swanson design) remains gold standard. Provides pain relief and improved appearance. ROM typically 30-40° post-op. Requires soft tissue balancing including extensor tendon centralization, intrinsic release, and collateral ligament reconstruction. Contraindicated in manual laborers.

Exam Pearl

Q: What differentiates osteoarthritis from rheumatoid arthritis at the MCP joint?

A: OA: Index/middle finger MCP involvement, osteophytes, subchondral sclerosis, preserved bone density. RA: Symmetric polyarticular involvement, periarticular osteopenia, marginal erosions, soft tissue swelling, ulnar drift. RA rarely affects DIP (contrast with OA which commonly affects DIP).

Exam Pearl

Q: What is the role of MCP arthrodesis versus arthroplasty?

A: Arthrodesis preferred for: thumb MCP (requires stability for pinch), single-digit involvement, young laborers, post-traumatic arthritis. Arthroplasty preferred for: Multiple digit RA involvement (maintains finger cascade motion). Arthrodesis position: Index 25°, middle 30°, ring 35°, small 40° flexion.

Exam Pearl

Q: What soft tissue procedure is essential during MCP arthroplasty for rheumatoid arthritis?

A: Extensor tendon centralization - the extensor tendons must be relocated from their ulnarly subluxed position over the MCP joint center. Techniques include: radial sagittal band repair, crossed intrinsic transfer, juncturae release. Without centralization, ulnar drift recurs post-operatively.

Australian Context

Australian Clinical Guidelines:

  • RACS (Royal Australasian College of Surgeons) supports silicone MCP arthroplasty for rheumatoid MCP arthritis with deformity and failed medical management
  • Thumb MCP arthrodesis preferred over arthroplasty for post-traumatic arthritis (evidence-based)
  • DMARD therapy coordinated with rheumatology is first-line for rheumatoid disease (defer surgery until medical management optimized)
  • Biologics (anti-TNF, IL-6 inhibitors) reserved for moderate-severe RA uncontrolled on traditional DMARDs

PBS (Pharmaceutical Benefits Scheme):

  • DMARDs: Methotrexate, sulfasalazine (PBS-subsidized for RA, requires rheumatology or GP prescription)
  • Biologics: Adalimumab (Humira), etanercept (Enbrel), tocilizumab (Actemra) - PBS Authority required, restricted to rheumatology prescription, requires failed MTX trial
  • NSAIDs: Ibuprofen, celecoxib (PBS-subsidized)
  • Corticosteroids: Prednisone (PBS-subsidized)

eTG (Therapeutic Guidelines - Antibiotic):

  • Perioperative prophylaxis for MCP arthroplasty: Cefazolin 2g IV (or cefalotin 2g IV) within 60 minutes of incision, single dose
  • Penicillin allergy: Vancomycin 15-20mg/kg IV OR clindamycin 600mg IV
  • Prosthetic joint infection: Consult infectious disease, typically 6 weeks IV antibiotics (culture-directed)

Medicolegal Considerations:

  • Informed consent: Document failed conservative management (DMARDs, biologics, injections, splinting for greater than 3-6 months)
  • Realistic expectations: Counsel that silicone arthroplasty provides 30-40 degrees ROM (not full), implant fracture risk 5-10%, recurrent deformity 10-15%, stiffness common
  • Post-operative compliance: Emphasize dynamic splinting for 6 weeks is critical (document patient understanding)
  • Coordination with rheumatology: Perioperative DMARD management (hold biologics 1-2 half-lives pre-op, restart when wound healed)
  • Smoking cessation: Document counseling (impairs fusion for arthrodesis, increases infection risk)

Hand Therapy Availability:

  • Certified hand therapists (CHT) essential for post-operative dynamic splinting fabrication and supervision
  • Available in major Australian cities (Sydney, Melbourne, Brisbane, Perth)
  • Custom dynamic MCP extension splints fabricated by hand therapist (critical for preventing recurrent ulnar drift)
  • Intensive therapy for 3-6 months recommended to optimize outcomes
  • Medicare rebate available for occupational therapy services

Rheumatology Collaboration:

  • Close coordination with rheumatology for DMARD/biologic management
  • Hold anti-TNF agents 1-2 half-lives pre-operatively (e.g., adalimumab hold 2-4 weeks)
  • Restart biologics when surgical wound healed (typically 2 weeks post-op)
  • Methotrexate: Some hold 1 week pre-op, others continue (discuss with rheumatology)
  • Perioperative corticosteroid stress dosing if on chronic prednisone (adrenal suppression)

MCP JOINT ARTHRITIS

High-Yield Exam Summary

Etiology and Epidemiology

  • •Rheumatoid arthritis: 90% of RA patients have MCP involvement (most common cause)
  • •Post-traumatic: Following MCP fracture, dislocation, ligament injury (unilateral, single digit)
  • •Primary OA: Rare at MCP (unlike CMC-1, DIP, PIP)
  • •Psoriatic/crystalline: Seronegative spondyloarthropathy, gout, pseudogout
  • •Female greater than male 3:1 (RA), peak onset 40-60 years

Rheumatoid MCP Pathomechanics (VUSEX)

  • •Volar subluxation: Proximal phalanx subluxes volarly from volar plate stretch
  • •Ulnar drift: Radial collateral ligament laxity, ulnar intrinsics pull ulnarly
  • •Synovitis: Primary event - chronic inflammation stretches capsule and ligaments
  • •Extensor displacement: Tendons displace ulnarly into valleys (sagittal band attenuation)
  • •X-ray: Shows volar subluxation (lateral view) and ulnar deviation (PA view)

Nalebuff Rheumatoid Hand Classification

  • •Type I: Swan-neck (MCP flexion, PIP hyperextension, DIP flexion) - most common
  • •Type II: Boutonniere (MCP hyperextension, PIP flexion, DIP hyperextension)
  • •Type III: Combined MCP ulnar drift with swan-neck deformity
  • •Type IV: Severe MCP volar subluxation (end-stage rheumatoid destruction)

Imaging and Larsen Grading

  • •Larsen Grade I: Periarticular swelling, osteopenia, no erosions (non-operative)
  • •Larsen Grade II: Erosions, joint space narrowing less than 50%
  • •Larsen Grade III-V: Severe erosions, narrowing greater than 50%, subluxation (SURGICAL)
  • •PA and lateral hand x-rays: Assess ulnar drift, volar subluxation, erosions
  • •Post-traumatic: Joint space narrowing, subchondral sclerosis, osteophytes

Non-Operative Management

  • •DMARDs: Methotrexate first-line (10-25mg weekly), sulfasalazine, leflunomide
  • •Biologics: Anti-TNF (adalimumab, etanercept), IL-6 inhibitors (tocilizumab), JAK inhibitors (moderate-severe RA)
  • •NSAIDs: Symptomatic relief only, do NOT modify disease
  • •Injections: Corticosteroid (triamcinolone 20mg), 50-70% relief for 3-6 months
  • •Splinting: MCP ulnar drift orthosis (slows progression, does NOT reverse deformity)

Silicone MCP Arthroplasty (Digits 2-5)

  • •Indications: Rheumatoid MCP arthritis, digits 2-5 (NOT thumb), failed medical management
  • •Implant: Silicone elastomer spacer (Swanson, Sutter, NeuFlex), NOT load-bearing
  • •Technique: Resect MC head, ream canals, insert implant with stems into MC and phalanx
  • •Adjuncts (ESSENTIAL): Synovectomy, extensor centralization, radial collateral ligament reconstruction, intrinsic release
  • •Post-op: Dynamic MCP extension splint 6 weeks full-time (CRITICAL for preventing recurrent drift)
  • •Outcomes: 30-40 degrees ROM, 80-90% at 10 years survivorship, 85% pain relief

MCP Arthrodesis (Preferred for Thumb)

  • •Indications: Thumb MCP arthritis (post-traumatic or RA), post-traumatic digits 2-5 with bone loss, failed arthroplasty
  • •Fusion position: Thumb 10-15 degrees flexion, Index 25-30, Middle 35-40, Ring 40-45, Small 45-50 (cascading flexion)
  • •Fixation: Dorsal locking plate preferred (rigid, 95% fusion rate), K-wires alternative
  • •Rationale for thumb: Pinch stability essential (high loads 5-10x pinch force), arthroplasty risks instability
  • •Outcomes: 95% fusion rate, excellent pain relief, stable pinch, high satisfaction

Soft Tissue Adjunct Procedures

  • •Extensor tendon centralization: Reposition extensor over MCP center, suture to radial capsule
  • •Radial collateral ligament reconstruction: Reef radial structures, correct ulnar drift
  • •Ulnar intrinsic release: Release tight ulnar interosseous from proximal phalanx
  • •Crossed intrinsic transfer: Transfer ulnar lateral band to radial side (severe recurrent drift)
  • •WITHOUT soft tissue balancing, arthroplasty WILL fail (recurrent ulnar drift)

Post-operative Protocol

  • •Dynamic MCP extension splint: 6 weeks full-time, then night splinting 3 months
  • •Immediate passive ROM: Day 1-2 with dynamic splint (flexion allowed, extension assisted)
  • •Active ROM: Week 6 (after splint removed during day)
  • •Strengthening: Week 12 (gentle grip, progressive resistance)
  • •Hand therapy: Certified hand therapist essential for splint fabrication and supervision

Complications

  • •Implant fracture: 5-10% (often asymptomatic due to fibrous encapsulation, observe if pain-free)
  • •Recurrent ulnar drift: 10-15% (inadequate soft tissue balancing at index surgery)
  • •Stiffness: 20-30% (hand therapy essential, dynamic splinting, tenolysis if severe)
  • •Subsidence: 5% (implant sinks into bone, observe if mild)
  • •Infection: Less than 2% (early: wash-out, antibiotics; late: implant removal, staged fusion)
  • •Nonunion (arthrodesis): 5-10% (revision with bone graft and rigid plate)

Thumb vs Fingers Decision

  • •Thumb MCP: Arthrodesis preferred (pinch stability, 10-15 degrees flexion)
  • •Digits 2-5: Silicone arthroplasty preferred (motion needed for grip function)
  • •DO NOT fuse multiple MCPs bilaterally (eliminates grip function)
  • •Thumb arthroplasty risks instability under pinch loads (silicone not load-bearing)

Exam Pearls (High Yield)

  • •VUSEX: Volar subluxation, Ulnar drift, Synovitis, Extensor displacement, X-ray (rheumatoid mechanism)
  • •SPACER: Silicone acts as spacer, not load-bearing hinge (Preserves motion, Alignment, Centralize extensors, Encapsulation, Release intrinsics)
  • •CASCADE: Cascading MCP fusion angles (Thumb 10-15, Index 25-30, Middle 35-40, Ring 40-45, Small 45-50)
  • •Silicone arthroplasty REQUIRES soft tissue balancing (extensor centralization, ligament reconstruction, intrinsic release)
  • •Dynamic MCP extension splinting for 6 weeks is CRITICAL (prevents recurrent ulnar drift)
Quick Stats
Reading Time186 min
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