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Musculoskeletal Ultrasound

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Musculoskeletal Ultrasound

Comprehensive guide to musculoskeletal ultrasound physics, technique, normal appearances, and orthopaedic applications including tendon, muscle, and joint assessment.

High Yield
complete
Updated: 2026-01-16
High Yield Overview

Musculoskeletal Ultrasound

Real-Time Dynamic Imaging

7-15MHzMSK Probe Frequency
0Ionizing Radiation
Real-timeDynamic Assessment
93%Sensitivity for Full-Thickness RC Tears

Tissue Echogenicity

Hyperechoic (Bright)
PatternBone cortex, calcification, fibrous tissue
TreatmentStrong reflection
Isoechoic
PatternSimilar to surrounding tissue
TreatmentReference
Hypoechoic (Dark)
PatternMuscle, some fluid, pathology
TreatmentPartial transmission
Anechoic (Black)
PatternSimple fluid, blood vessels
TreatmentComplete transmission
Acoustic Shadow
PatternBehind bone, calcification
TreatmentNo transmission

Critical Must-Knows

  • Frequency determines resolution: Higher frequency = better resolution but less penetration.
  • Anisotropy: Tendons appear artifactually hypoechoic when beam is not perpendicular.
  • Normal tendon: Fibrillar hyperechoic pattern with parallel echogenic lines.
  • Effusion: Anechoic or hypoechoic fluid distending joint capsule/bursa.
  • Dynamic assessment: Can stress structures and assess in real-time (snap, subluxation).

Examiner's Pearls

  • "
    Always compare with contralateral side for normal reference.
  • "
    Anisotropy artifact mimics pathology - adjust probe angle to confirm.
  • "
    Rotator cuff US has 90%+ accuracy for full-thickness tears in experienced hands.
  • "
    US-guided injection improves accuracy compared to landmark technique.
  • "
    Doppler shows increased vascularity in tendinopathy and inflammation.

Clinical Imaging

Imaging Gallery

New imaging modalities for demonstrating serum urate deposition.(A) Musculoskeletal ultrasound of a first metatarsal phalangeal joint (plantar longitudinal view) demonstrating a classic “double contou
Click to expand
New imaging modalities for demonstrating serum urate deposition.(A) Musculoskeletal ultrasound of a first metatarsal phalangeal joint (plantar longituCredit: Open-i / NIH via Open-i (NIH) (Open Access (CC BY))
Semiquantitative ultrasound score in B-mode at the wrist joint in the central dorsal longitudinal position (A) and color Doppler semiquantitative ultrasound at the metacarpophalangeal (MCP) joints in
Click to expand
Semiquantitative ultrasound score in B-mode at the wrist joint in the central dorsal longitudinal position (A) and color Doppler semiquantitative ultrCredit: Rezaei H et al. via Arthritis Res. Ther. via Open-i (NIH) (Open Access (CC BY))
Examples of HRUS pathologies of the shoulder (43, 44)A. Shoulder lateral longitudinal view. No pathology. M. supraspinatus tendon (star), humerus (triangle). B. Shoulder anterior transverse view. Burs
Click to expand
Examples of HRUS pathologies of the shoulder (43, 44)A. Shoulder lateral longitudinal view. No pathology. M. supraspinatus tendon (star), humerus (triCredit: Micheroli R et al. via J Ultrason via Open-i (NIH) (Open Access (CC BY))
Ultrasound images of hands in Case 3 before and after treatment. Shown are the representative ultrasound images of the left hand before treatment (a–d) and after 24 weeks of abatacept treatment (e–h).
Click to expand
Ultrasound images of hands in Case 3 before and after treatment. Shown are the representative ultrasound images of the left hand before treatment (a–dCredit: Ikeda K et al. via Clin. Dev. Immunol. via Open-i (NIH) (Open Access (CC BY))

Operator Dependence

Ultrasound accuracy is highly operator-dependent. Systematic technique, knowledge of anatomy, and experience are essential. In expert hands, MSK ultrasound approaches MRI accuracy for many soft tissue conditions, but results vary significantly with operator skill.

Physics Fundamentals

Sound Wave Principles

  1. Frequency: Number of cycles per second (Hz). MSK uses 7-15 MHz (high frequency).
  2. Wavelength: Distance between wave peaks. Shorter wavelength = better resolution.
  3. Velocity: Speed of sound in tissue (approximately 1540 m/s in soft tissue).

Resolution vs Penetration Trade-off

Frequency Selection

FrequencyResolutionPenetrationApplication
5-7 MHzLowerDeeper (10-15cm)Hip, deep structures
7-12 MHzMediumMedium (5-7cm)Shoulder, knee, ankle
12-15 MHzHigherSuperficial (3-4cm)Hand, foot, superficial tendons
15-18 MHzHighestVery superficialFinger tendons, nerves

Tissue Interactions

Reflection

Sound bounces back at tissue interfaces. Greater impedance difference = stronger reflection. Creates the image.

Transmission

Sound passes through tissue. Fluids transmit well (posterior enhancement). Bone blocks transmission (shadowing).

Refraction

Sound bends at angled interfaces. Can cause positional errors.

Attenuation

Sound energy decreases with depth. Higher frequency = more attenuation.

Equipment & Technique

Probe Selection

Ultrasound Probes for MSK

Probe TypeFrequencyBest For
Linear High-Frequency10-15 MHzSuperficial tendons, nerves, small joints
Linear Standard7-12 MHzShoulder, knee, ankle, medium-depth structures
Curvilinear3-5 MHzHip, deep muscles, obese patients
Hockey Stick12-15 MHzFingers, toes, small superficial structures

Scanning Technique

Mnemonic

CALMSystematic MSK Ultrasound

C
Compare
Always scan contralateral side for comparison
A
Anisotropy
Adjust probe angle to avoid false hypoechogenicity
L
Long and Short
Scan in both longitudinal and transverse planes
M
Move
Dynamic assessment - move the joint, stress the structure

Memory Hook:Stay CALM and scan systematically

Key Technical Points

  • Gel: Adequate coupling gel eliminates air interface
  • Probe pressure: Light pressure for superficial structures, firm for deep
  • Gain: Adjust so fluid is black, normal tissue is grey
  • Depth: Set to visualize structure of interest plus some background
  • Focus: Position at level of structure of interest

Anisotropy

Understanding Anisotropy

Anisotropy is the most important artifact in MSK ultrasound. Tendons have highly organized parallel collagen fibers that reflect sound optimally when the beam is perpendicular.

Perpendicular Beam

  • Sound reflects back to probe
  • Tendon appears normally hyperechoic
  • Fibrillar pattern visible
  • TRUE appearance

Oblique Beam

  • Sound reflects away from probe
  • Tendon appears artifactually hypoechoic
  • May mimic tear or tendinopathy
  • FALSE appearance (artifact)

Avoiding Anisotropy Errors

  1. Heel-toe maneuver: Rock probe to find perpendicular angle
  2. Dynamic assessment: Real pathology stays abnormal, anisotropy corrects
  3. Contralateral comparison: If both sides look the same, likely technique
  4. Orthogonal views: Pathology visible in multiple planes

Normal Appearances

Tissue Echogenicity

Normal Tissue Appearances

TissueEchogenicityPatternNotes
TendonHyperechoicFibrillar (parallel lines)Affected by anisotropy
MuscleHypoechoicPennate (feather-like)Hyperechoic fascia/perimysium
NerveHypoechoicFascicular (honeycomb in short axis)Less anisotropic than tendon
LigamentHyperechoicCompact fibrillarMore compact than tendon
CartilageHypoechoicHomogeneousThin layer over bone
BoneHyperechoicBright line + shadowOnly cortex visible
FluidAnechoicBlack, compressiblePosterior enhancement

Important Artifacts

Posterior Acoustic Enhancement

Brightness deep to fluid-filled structures (cysts, vessels). Confirms fluid content.

Acoustic Shadowing

Dark area deep to highly reflective structures (bone, calcification). Confirms dense material.

Reverberation

Multiple parallel lines deep to strong reflector or superficial to needle. Common with metal.

Edge Artifact

Shadow at curved surfaces (vessel edges, cyst margins). Normal finding.

Orthopaedic Applications

Tendon Pathology

Full-Thickness Tear:

  • Complete discontinuity of tendon fibers
  • Hypoechoic/anechoic gap
  • Retraction of torn ends
  • Non-visualization of tendon

Partial-Thickness Tear:

  • Focal hypoechoic defect not extending full thickness
  • Surface irregularity (articular or bursal)
  • Thinning of tendon

Features:

  • Tendon thickening (compare to other side)
  • Hypoechoic areas within tendon
  • Loss of normal fibrillar pattern
  • Increased Doppler signal (neovascularization)
  • May have calcification

Calcific Tendinopathy:

  • Hyperechoic focus within tendon
  • Variable shadowing (depends on calcium type)
  • Soft calcium: Less defined, less shadow
  • Hard calcium: Well-defined, strong shadow

Joint Assessment

Effusion

  • Anechoic or hypoechoic fluid
  • Distends joint capsule
  • Compressible with probe pressure
  • Compare to normal side

Common locations: Knee (suprapatellar), hip (anterior), shoulder (posterior), ankle

Synovitis

  • Thickened synovium (hypoechoic)
  • Non-compressible (unlike fluid)
  • Increased Doppler signal
  • May have frond-like projections

Seen in: RA, inflammatory arthritis, infection

Regional Applications

Regional Ultrasound Applications

RegionKey StructuresCommon Pathology
ShoulderRotator cuff, biceps, bursaRC tears, biceps tendinopathy, bursitis
ElbowCommon extensor/flexor, ulnar nerveLateral epicondylitis, cubital tunnel
Wrist/HandTendons, carpal tunnel, TFCCDeQuervain, CTS, trigger finger
HipLabrum (limited), tendons, bursaeTrochanteric bursitis, effusion (children)
KneeQuadriceps, patellar tendon, collateralsTendinopathy, Bakers cyst, MCL injury
Ankle/FootAchilles, peroneals, plantar fasciaAchilles pathology, plantar fasciitis

US-Guided Procedures

Advantages of US guidance:

  • Real-time needle visualization
  • Improved accuracy vs landmark technique
  • Avoid vessels and nerves
  • Confirm medication delivery

Common procedures:

  • Joint injection (shoulder, hip, knee)
  • Bursa injection (subacromial, trochanteric)
  • Tendon sheath injection (DeQuervain, trigger finger)
  • Aspiration (cyst, effusion, abscess)
  • Calcific barbotage

Doppler Imaging

Doppler Modes

Color Doppler

  • Shows flow direction and velocity
  • Red toward probe, blue away (usually)
  • Useful for identifying vessels
  • Assessing vascularity in masses/inflammation

Power Doppler

  • More sensitive to slow flow
  • No directional information
  • Better for small vessel detection
  • Useful for synovitis, tendinopathy vascularity

Clinical Applications

  • Inflammation: Increased Doppler signal in synovitis, tendinopathy
  • Tumor: Vascularity assessment (malignancy often hypervascular)
  • Infection: Hyperemia in cellulitis, abscess rim
  • Post-treatment: Response monitoring (Doppler should decrease)

US vs MRI

Ultrasound vs MRI for MSK

FeatureUltrasoundMRI
CostLowerHigher
AvailabilityHigh, portableLimited, fixed
RadiationNoneNone
Dynamic assessmentExcellentLimited
Bone marrowCannot assessExcellent
Deep structuresLimitedExcellent
Operator dependenceHighLower
Interventional guidanceReal-timePossible but complex
CartilageLimited (surface only)Excellent
Rotator cuff tears90%+ accuracy (expert)95%+ accuracy

Exam Viva Scenarios

Practice these scenarios to excel in your viva examination

VIVA SCENARIOStandard

Ultrasound Physics Viva

EXAMINER

"Explain the concept of anisotropy and why it's important in musculoskeletal ultrasound."

EXCEPTIONAL ANSWER
Anisotropy is an artifact that occurs because tendons have highly organized parallel collagen fibers that reflect ultrasound optimally only when the beam is perpendicular to the fibers. When the probe is angled obliquely, sound reflects away from the transducer rather than back to it, causing the tendon to appear artifactually hypoechoic or even anechoic - mimicking pathology such as a tear or tendinopathy. This is the most common pitfall in MSK ultrasound. To avoid this error, I always use the heel-toe maneuver to find the optimal perpendicular angle, confirm findings in multiple planes, perform dynamic assessment, and compare with the contralateral side. True pathology will appear abnormal regardless of probe angle, while anisotropy artifact will correct when the probe is properly aligned.
KEY POINTS TO SCORE
Anisotropy = artifact from oblique beam angle
Tendons appear falsely hypoechoic when beam not perpendicular
Heel-toe maneuver to find optimal angle
Compare to other side and use dynamic assessment
COMMON TRAPS
✗Not mentioning how to distinguish from real pathology
✗Forgetting that this affects tendons more than other tissues
✗Not explaining the underlying physics
LIKELY FOLLOW-UPS
"What other artifacts are common in MSK ultrasound?"
"How does frequency affect resolution and penetration?"
"When would you use Doppler in MSK imaging?"
VIVA SCENARIOStandard

Rotator Cuff Assessment

EXAMINER

"How do you assess the rotator cuff with ultrasound and what findings indicate a full-thickness tear?"

EXCEPTIONAL ANSWER
I assess the rotator cuff systematically using a high-frequency linear probe (10-15 MHz). I examine the subscapularis in internal rotation, the biceps tendon in the bicipital groove, and the supraspinatus and infraspinatus in the modified Crass position (hand on ipsilateral back pocket). I compare to the other side. For supraspinatus, the normal tendon appears hyperechoic with a fibrillar pattern, convex superficially (beak sign). Full-thickness tear findings include: complete discontinuity of the tendon, a hypoechoic or anechoic gap, non-visualization of the tendon, retraction of the torn ends, and herniation of the deltoid muscle toward the humeral head. Indirect signs include cartilage interface sign (fluid at bare area) and loss of the subdeltoid bursa-supraspinatus interface. Sensitivity for full-thickness tears is 92-95% in experienced hands.
KEY POINTS TO SCORE
Systematic examination: subscapularis, biceps, supraspinatus, infraspinatus
Modified Crass position for supraspinatus
Full-thickness tear: discontinuity, anechoic gap, retraction
Compare to contralateral side
COMMON TRAPS
✗Forgetting to assess all four rotator cuff tendons
✗Not mentioning patient positioning
✗Confusing anisotropy artifact with tear
LIKELY FOLLOW-UPS
"How do you differentiate partial from full-thickness tears?"
"What is the accuracy of US compared to MRI for rotator cuff?"
"When would you prefer MRI over ultrasound?"
VIVA SCENARIOStandard

US-Guided Injection

EXAMINER

"What are the advantages of ultrasound-guided injection over landmark technique?"

EXCEPTIONAL ANSWER
Ultrasound-guided injection offers several advantages over landmark technique. First, improved accuracy - studies show significantly higher rates of correct needle placement, particularly for small joints and bursae. For example, landmark glenohumeral injection is accurate only 50-70% of the time, while US-guided approaches are greater than 90% accurate. Second, real-time visualization allows me to see the needle path, avoid neurovascular structures, and confirm delivery of medication to the target. Third, I can visualize pathology before injection and potentially aspirate fluid for analysis. Fourth, it allows access to difficult targets like hip joints, which are too deep for reliable landmark technique. Finally, patient safety is improved by avoiding vessels and nerves. The main disadvantage is the need for equipment and training. For large superficial joints like the knee, landmark technique may be adequate, but for deeper or more technically challenging targets, ultrasound guidance is preferred.
KEY POINTS TO SCORE
Improved accuracy vs landmark (90% vs 50-70%)
Real-time needle visualization
Avoid neurovascular structures
Confirm medication delivery to target
COMMON TRAPS
✗Not mentioning specific accuracy data
✗Forgetting that landmark is acceptable for some joints
✗Not discussing any limitations of US guidance
LIKELY FOLLOW-UPS
"How do you visualize the needle tip during injection?"
"What structures would you inject under US guidance?"
"What are the complications of joint injection?"

MSK Ultrasound Exam Day Cheat Sheet

High-Yield Exam Summary

Physics Basics

  • •Higher frequency = better resolution, less penetration
  • •MSK uses 7-15 MHz linear probes
  • •Anisotropy = artifact from oblique beam angle
  • •Always compare to contralateral side

Tissue Echogenicity

  • •Tendon: Hyperechoic, fibrillar pattern
  • •Muscle: Hypoechoic, pennate pattern
  • •Nerve: Hypoechoic, fascicular/honeycomb
  • •Fluid: Anechoic (black), compressible

Pathology Features

  • •Full-thickness tear: Discontinuity, anechoic gap
  • •Tendinopathy: Thickening, hypoechoic, loss of fibrillar pattern
  • •Effusion: Anechoic fluid, distends capsule
  • •Synovitis: Thickened, non-compressible, Doppler positive

US vs MRI

  • •US: Dynamic, portable, real-time guidance, cheaper
  • •US cannot assess: Bone marrow, deep structures, cartilage detail
  • •RC tear accuracy: US 92-95%, MRI 95%+
  • •US is operator-dependent
Quick Stats
Reading Time47 min
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