WEAR MECHANISMS IN ORTHOPAEDICS
Adhesive | Abrasive | Fatigue | Third-Body
Wear Types
Critical Must-Knows
- Polyethylene wear debris causes particle-induced osteolysis via macrophage activation
- Cross-linking reduces polyethylene wear by 50-90% but may reduce mechanical properties
- Ceramic-on-ceramic has lowest volumetric wear but risk of fracture and squeaking
- Third-body wear from cement, bone, or metal particles accelerates bearing damage
- Wear threshold: historic 2mm/year PE wear associated with osteolysis risk
Examiner's Pearls
- "Adhesive = cold welding, material transfer
- "Abrasive = harder scratches softer (two-body or three-body)
- "Fatigue (delamination) = subsurface crack propagation
- "Particle size 0.1-1μm most biologically active for osteolysis
Critical Wear Mechanism Exam Points
Wear Types (AAFT)
Adhesive: Cold welding and transfer. Abrasive: Scratching. Third-body: Trapped particles. Fatigue: Subsurface cracks from cyclic loading (delamination in PE).
Particle-Induced Osteolysis
Wear particles activate macrophages → release cytokines (IL-1, TNF-α) → stimulate osteoclasts → bone resorption around implant → loosening. Particle size 0.1-1μm most inflammatory.
HXLPE Benefits
Highly cross-linked polyethylene (radiation, remelting/annealing) reduces wear 50-90%. Trade-off: reduced toughness and fracture resistance. Standard for hip, gaining use in knee.
Bearing Combinations
MoP: Metal-on-poly, standard, improved with HXLPE. CoC: Ceramic-on-ceramic, lowest wear but fracture/squeak risk. MoM: Abandoned due to metal ions. CoP: Ceramic-on-poly, low wear.
At a Glance
Four primary wear mechanisms affect orthopaedic bearings: adhesive (cold welding and material transfer), abrasive (harder surface scratches softer), fatigue/delamination (subsurface crack propagation from cyclic loading), and third-body (trapped particles accelerate wear). Polyethylene wear debris causes particle-induced osteolysis via macrophage activation and cytokine release (IL-1, TNF-α) stimulating osteoclasts—particles 0.1-1μm are most biologically active. Highly cross-linked polyethylene (HXLPE) reduces wear by 50-90% but with reduced toughness. Bearing combinations: MoP (metal-on-poly, improved with HXLPE), CoC (ceramic-on-ceramic, lowest wear but fracture/squeak risk), CoP (ceramic-on-poly), and MoM (abandoned due to metal ion concerns). Historic threshold: over 2mm/year PE wear associated with osteolysis risk.
AAFTWear Types
Memory Hook:AAFT = Adhesive, Abrasive, Fatigue, Third-body - the four wear mechanisms!
POMOOsteolysis Pathway
Memory Hook:POMO = Particles → macrophages (Opsonize) → Mediators → Osteolysis!
Overview
Wear is the progressive loss of material from articulating surfaces due to mechanical action. In orthopaedic joint replacement, wear generates debris that can cause adverse biological reactions (osteolysis) leading to implant loosening and revision surgery.
Clinical Significance
- Primary cause of long-term arthroplasty failure
- Polyethylene wear debris triggers osteolysis
- Drives bearing surface material development
- HXLPE has dramatically improved outcomes
Mechanisms and Types
Adhesive Wear
Definition: Wear resulting from adhesion (cold welding) between asperities of two surfaces, followed by material transfer.
Mechanism:
- High local pressure at asperity contact points
- Local adhesion (micro-welding) between surfaces
- Relative motion shears the junction
- Material transfers from weaker to stronger surface
- Transferred material may detach as debris
Factors:
- Surface finish quality
- Lubrication (synovial fluid)
- Material hardness mismatch
- Contact pressure
Clinical Examples:
- Metal-on-metal bearings (historic)
- Poorly lubricated interfaces
- Run-in wear in new implants
Prevention:
- Good surface finish
- Adequate lubrication
- Material selection (CoCr or ceramic heads)
Bearing Surface Anatomy
Articulating Surfaces
Hip Arthroplasty:
- Femoral head (CoCr, ceramic, or oxinium)
- Acetabular liner (PE, ceramic, or metal)
- Modular junction (head-neck trunnion)
Knee Arthroplasty:
- Femoral component (CoCr)
- Tibial insert (polyethylene)
- Patellofemoral articulation
Bearing Combinations
| Combination | Head | Cup/Insert |
|---|---|---|
| MoP | CoCr or ceramic | Polyethylene |
| CoC | Ceramic | Ceramic |
| CoP | Ceramic | Polyethylene |
| MoM | CoCr | CoCr (abandoned) |
Classification
Wear Mechanism Types (AAFT)
Four Primary Mechanisms:
Wear Type Classification
| Type | Mechanism | Example |
|---|---|---|
| Adhesive | Cold welding, material transfer | MoM bearings |
| Abrasive | Scratching by harder surface | Damaged CoCr head |
| Fatigue | Subsurface cracks, delamination | Gamma-sterilized PE |
| Third-body | Trapped particles accelerate wear | Cement debris |
Clinical Relevance - Particle Disease
Particle-Induced Osteolysis
Pathophysiology:
- Wear particles generated at bearing surfaces
- Macrophages attempt to phagocytose particles
- Particles too large or resistant to digestion
- Frustrated phagocytosis activates macrophages
- Release of pro-inflammatory cytokines (IL-1, TNF-α, IL-6)
- Cytokines stimulate osteoclast differentiation (RANK-RANKL)
- Osteoclastic bone resorption around implant
- Progressive osteolysis leads to loosening
Particle Characteristics:
- Size 0.1-1μm most biologically active
- Larger particles less inflammatory (cannot be phagocytosed)
- Smaller particles - billions generated, cumulative effect
- Material: PE > metal > ceramic (in terms of volume)
Clinical Manifestations:
- Often asymptomatic until advanced
- Radiolucent lesions on radiographs
- Progressive loosening
- Pathological periprosthetic fracture
Investigations
Assessment of Wear
Radiographic Evaluation:
- Serial radiographs for PE wear measurement
- Measure from femoral head center to acetabular rim
- Compare to baseline post-op films
Key Findings:
- Linear wear rate (mm/year)
- Eccentric head position
- Osteolytic lesions (radiolucent areas)
Imaging Modalities
| Modality | Purpose | Findings |
|---|---|---|
| X-ray | Wear measurement | Linear wear, osteolysis |
| CT | Osteolysis quantification | 3D bone loss assessment |
| MARS-MRI | Soft tissue assessment | ALVAL, pseudotumor |
Management

Management Approach
Surveillance:
- Asymptomatic wear: Serial monitoring
- Annual or biannual radiographs
- Assess for progressive osteolysis
Intervention Thresholds:
- Symptomatic loosening
- Progressive osteolysis
- High wear rate with HXLPE available
Management Options
| Situation | Approach | Rationale |
|---|---|---|
| Early wear, stable | Observe, serial X-rays | May stabilize |
| Significant osteolysis | Plan revision | Prevent bone loss |
| Symptomatic loosening | Revision arthroplasty | Address failure |
Revision Surgical Technique
Revision Approach
Options:
- Isolated liner exchange: Well-fixed cup, adequate bone
- Cup revision: Loose cup or insufficient bone
- Stem revision: If loose or corroded trunnion
Liner Exchange:
- Remove liner, debride membrane
- Bone graft osteolytic lesions
- Insert new HXLPE liner
Revision Options
| Procedure | Indication | Complexity |
|---|---|---|
| Liner exchange | Well-fixed cup, good bone | Moderate |
| Cup revision | Loose or poor bone stock | Major |
| Full revision | Both components involved | Complex |
Complications
Wear-Related Complications
Biological:
- Particle-induced osteolysis
- Aseptic loosening
- Periprosthetic fracture
Material-Specific:
- Polyethylene: Osteolysis, loosening
- Metal: ALVAL, pseudotumor, metallosis
- Ceramic: Fracture, squeaking
Complications by Material
| Material | Complication | Incidence |
|---|---|---|
| Conventional PE | Osteolysis | 10-20% at 10 years |
| HXLPE | Osteolysis | Less than 5% at 10 years |
| Ceramic | Fracture | Less than 0.1% |
| MoM | ALVAL | 5-10% (abandoned) |
Postoperative Care
After Revision Surgery
Immediate:
- Standard THA precautions
- Protected weight-bearing if bone grafted
- VTE prophylaxis
Follow-up:
- Serial radiographs to assess bone healing
- Monitor for osteolysis resolution
- Long-term surveillance
Recovery Timeline
| Timeframe | Weight-Bearing | Activity |
|---|---|---|
| 0-6 weeks | Protected if bone graft | Hip precautions |
| 6-12 weeks | Progress to full | Rehabilitation |
| 3+ months | Full activities | Long-term monitoring |
Outcomes
Modern Bearing Outcomes
HXLPE Results:
- 95-98% survivorship at 10-15 years
- Dramatic reduction in osteolysis
- Lower revision rates than conventional PE
Ceramic-on-Ceramic:
- 97-99% survivorship at 10 years
- Lowest wear rates
- Rare fracture/squeaking
Bearing Survivorship
| Bearing | 10-Year Survival | Key Advantage |
|---|---|---|
| MoP (HXLPE) | 95-98% | Low wear, proven |
| CoC | 97-99% | Lowest wear |
| CoP | 96-98% | Low wear, no squeak |
| MoP (conv) | 85-90% | Abandoned for HXLPE |
Evidence Base
- Long-term Charnley THR follow-up
- PE wear rate correlated with osteolysis
- Established wear as primary failure mechanism
- Foundation for wear-focused research
- Early HXLPE outcomes very promising
- Significant wear reduction documented
- No increase in osteolysis with HXLPE
- Mechanical concerns (rim fracture) noted
- Particle size 0.1-1μm most inflammatory
- Volume of debris determines biological response
- UHMWPE generates billions of particles annually
- Cross-linking reduces particle number dramatically
Exam Viva Scenarios
Practice these scenarios to excel in your viva examination
Scenario 1: Osteolysis Management
"A 65-year-old man presents with progressive periacetabular osteolysis 12 years after primary cemented THA. PE wear measures 3mm. He is minimally symptomatic. How do you manage him?"
MCQ Practice Points
Wear Types
Q: What are the four main types of wear in orthopaedic implants? A: Adhesive (cold welding), Abrasive (scratching), Fatigue (delamination), and Third-body (trapped particles). Remember AAFT.
Osteolysis Pathway
Q: What is the mechanism of particle-induced osteolysis? A: Wear particles are phagocytosed by macrophages → activated macrophages release cytokines (IL-1, TNF-α) → cytokines stimulate RANK-RANKL pathway → osteoclast activation → bone resorption.
HXLPE
Q: How does highly cross-linked polyethylene reduce wear? A: Cross-linking by irradiation creates bonds between polymer chains, reducing plastic deformation and adhesive/abrasive wear by 50-90%. Post-irradiation treatment (remelting/annealing/vit E) removes free radicals to prevent oxidation.
Australian Context
Australian Practice:
- AOANJRR data supports HXLPE performance
- Lower revision rates with modern bearings
- Ceramic-on-ceramic use common in young patients
Monitoring:
- Surveillance for wear and osteolysis in registry
- Radiographic review for PE wear measurement
- CT for osteolysis quantification when indicated
WEAR MECHANISMS
High-Yield Exam Summary
Wear Types (AAFT)
- •Adhesive: Cold welding and transfer
- •Abrasive: Scratching (two-body or three-body)
- •Fatigue: Subsurface cracks, delamination
- •Third-body: Trapped particles accelerate wear
Osteolysis Pathway
- •Particles → Macrophage phagocytosis
- •Cytokine release (IL-1, TNF-α)
- •RANK-RANKL → Osteoclast activation
- •Particle size 0.1-1μm most active
HXLPE
- •Cross-linking by irradiation
- •Remelting/annealing removes free radicals
- •Wear reduction 50-90%
- •Standard for hip, increasing in knee
Bearing Selection
- •MoP with HXLPE: Standard, proven
- •CoC: Lowest wear, fracture/squeak risk
- •CoP: Low wear, ceramic benefits
- •MoM: Abandoned (metal ions, ALVAL)